Endoscopy 2005; 37(6): 594-596
DOI: 10.1055/s-2005-861322
Case Report
© Georg Thieme Verlag KG Stuttgart · New York

Capsule Endoscopy Findings in Celiac Disease Associated Enteropathy-Type Intestinal T-cell Lymphoma

A.  M.  Joyce1 , D.  L.  Burns2 , P.  W.  Marcello3 , B.  Tronic4 , F.  J.  Scholz2
  • 1Gastroenterology Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
  • 2Tufts University School of Medicine, Lahey Clinic Medical Center Burlington, Massachusetts, USA
  • 3Department of Colorectal Surgery, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
  • 4Department of Pathology, Lahey Clinic Medical Center, Burlington, Massachusetts, USA
Further Information

Publication History

Submitted 17 November 2004

Accepted after Revision 10 December 2004

Publication Date:
03 June 2005 (online)

Abstract

Capsule endoscopy is a new technology developed to investigate diseases of the small intestine. It has been shown to be superior to current modalities such as small-bowel radiography and enteroscopy. We describe a patient with long-standing celiac disease who presented with abdominal pain, diarrhea, and weight loss, after many years on a gluten-free diet. The symptom complex and results from small-bowel radiography and computerized tomography raised concern about progression to lymphoma, and ultimately a laparoscopy and small-bowel resection were done for diagnosis. A capsule endoscopy was performed to assess the extent of the patient’s enteropathy-type intestinal T-cell lymphoma after three cycles of chemotherapy. We report the first use of capsule endoscopy in the setting of celiac disease associated enteropathy-type intestinal T-cell lymphoma. These endoscopic findings are correlated with those from gross and microscopic pathology and barium small-bowel radiography.

  • 1 Kastin D A, Buchman A L, Barrett T. et al . Strictures of Crohn’s disease diagnosed by video capsule endoscopy.  J Clin Gastroenterol. 2004;  38 346-349
  • 2 Delvaux M M, Saurin J C, Gaudin J L. et al . Comparison of wireless endoscopic capsule and push-enteroscopy in patients with obscure occult/overt digestive bleeding: results of a prospective, blinded, multicenter trial.  Gastrointest Endosc. 2002;  55 AB88
  • 3 Demedts I, Gevers A M, Hiele M. et al . Wireless capsule enteroscopy is superior to push enteroscopy for identification of small intestinal source of obscure gastrointestinal bleeding.  Gastrointest Endosc. 2002;  55 AB146
  • 4 Jensen D M, Dulai G, Lousvebsakul V. et al . Diagnostic yield of capsule endoscopy in patients with severe GI bleeding of obscure origin, subsequent recommendations, and outcomes.  Gastrointest Endosc. 2002;  55 AB127
  • 5 Lo S K, Fisher H A, Tabibzaheh S. et al . Evaluation of bleeding of undetermined origin by wireless endoscopy.  Gastrointest Endosc. 2002;  55 AB129
  • 6 Pennazio M, Santucci R, Rondonotti E. et al . Wireless capsule endoscopy in patients with obscure GI bleeding: results of the Italian multicenter experience.  Gastrointest Endosc. 2002;  55 AB87
  • 7 Schulmann K, Hollerback S, Willert J. et al . Detection of occult gastrointestinal bleeding disorders by video capsule endoscopy (M2A) of the small bowel.  Gastroenterology. 2002;  122 A239
  • 8 Yousfi M, Sharma V K, Leighton J A. et al . Video capsule endoscopy (VCE) for obscure gastrointestinal bleeding (OGIB) and iron deficiency anemia (IDA).  Gastroenterology. 2002;  122 A18

A. M. Joyce, M. D.

Hospital of the University of Pennsylvania, Gastroenterology Division

3400 Spruce Street · 3 Ravdin Bldg. · Philadelphia · Pennsylvania 19104 · USA

Fax: +1-215-349-5915·

Email: ann.marie.joyce@uphs.upenn.edu