First Total Synthesis of the Irciniasulfonic Acids

Adrian P. Dobbs; Alberto Venturelli; Laura A. Butler; Robert J. Parker

doi:10.1055/s-2005-862387

LETTER

First Total Synthesis of the Irciniasulfonic Acids

Adrian P. Dobbs*^a, Alberto Venturelli^a,b, Laura A. Butler^a, Robert J. Parker^a
^a Department of Chemistry, University of Exeter, Stocker Road, Exeter, EX4 4QD, UK
Fax: +44(1392)263434; e-Mail: A.Dobbs@exeter.ac.uk;
^b Dipartimento di Scienze Farmaceutiche, Università degli Studi di Modena e Reggio Emilia, Via G. Campi n. 183, 41110 Modena, Italy

Abstract

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Abstract

A flexible and concise first total synthesis of the irciniasulfonic acids is reported.

Key words

total synthesis - irciniasulfonic acid - multidrug resistance modulator

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Referenzen

References

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13

All compounds gave satisfactory analytical and spectroscopic data. Compound data for the three natural products in good agreement with the values given in ref. 1.