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Planta Med 2005; 71(4): 355-361
DOI: 10.1055/s-2005-864103
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag KG Stuttgart · New York

Six New Triterpenoid Saponins from the Root and Stem Bark of Cephalanthus occidentalis

Zhizhen Zhang1 , Shiyou Li1 , Shanmin Zhang2
  • 1Center for Medicinal Plant Research, Arthur Temple College of Forestry, Stephen F. Austin State University, Nacogdoches, Texas, USA
  • 2Sealy Center for Structural Biology, Department of Physiology and Biophysics, University of Texas Medical Branch, Galveston, Texas, USA
Further Information

Publication History

Received: July 8, 2004

Accepted: October 14, 2004

Publication Date:
27 April 2005 (online)

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Abstract

From the root and stem bark of Cephalanthus occidentalis L., a common American wetland species, six new triterpenoid saponins (1 - 6), together with 29 known compounds were isolated and identified. On the basis of spectroscopic analysis and chemical degradation, the structures of new compounds were elucidated as 3-O-β-glucopyranosylcincholic acid (1), cincholic acid 28-O-β-glucopyranosyl ester (2), 3-O-β-glucopyranosyl-(1→4)-β-fucopyranosylcincholic acid (3), 3-O-β-glucopyranosyl-(1→4)-β-fucopyranosylcincholic acid 28-O-β-glucopyranosyl ester (4), 3-O-β-glucopyranosylcincholic acid 28-O-α-arabinopyranosyl-(1→2)-β-glucopyranosyl ester (5), and 3-O-β-glucopyranosylquinovic acid 28-O-α-arabinopyranosyl-(1→2)-β-glucopyranosyl ester (6).

Key words

Cephalanthus occidentalis - Rubiaceae - new triterpenoid saponins - alkaloids

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Shiyou Li, PhD

Center for Medicinal Plant Research

Arthur Temple College of Forestry

Stephen F. Austin State University

Nacogdoches

Texas 75962-6109

USA

Phone: +1-936-468-2071

Fax: +1-936-468-2489

Email: lis@sfasu.edu