Subscribe to RSS
DOI: 10.1055/s-2005-864127
Successful Treatment of Sexual Disinhibition in Dementia with Carbamazepine
A Case reportPublication History
Received: 3.8.2004
Revised: 4.11.2004
Accepted: 15.11.2004
Publication Date:
18 May 2005 (online)
Sexual disinhibition is a disturbing behavioral symptom in dementia. At present, there are no treatment guidelines available. Here we present the successful use of carbamazepine in a 78-year old AD patient with hypersexual behavior. The efficacy of carbamazepine in this case is in paralles to its effects on aggression and agitation in dementia and supports the important role of anticonvultsants in the management of behavioral disturbances in demented patients.
References
- 1 Alkhalil C, Tanvir F, Alkhalil B, Lowenthal D T. Treatment of sexual disinhibition in dementia: case reports and review of the literature. Am J Ther . 2004; 11 231-135
- 2 Amadeo M A. ntiandrogen treatment of aggressivity in men suffering from dementia. J Geriatr Psychiatry Neurol. 1996; 9 142-145
- 3 Azouvi P, Jokic C, Attal N, Denys P, Markabi S, Bussel B. Carbamazepine in agitation and aggressive behaviour following severe closed-head injury: results of an open trial. Brain Inj. 1999; 13 797-804
- 4 Bauer J, Blumenthal S, Reuber M, Stoffel-Wagner B. Epilepsy syndrome, focus location, and treatment choice affect testicular function in men with epilepsy. Neurology. 2004; 62 243-246
- 5 Derouesne C, Guigot J, Chermat V, Winchester N, Lacomblez L. Sexual behavioral changes in Alzheimer disease. Alzheimer Dis Assoc Disord. 1996; 10 86-92
- 6 Grossman F. A review of anticonvulsants in treating agitated demented elderly patients. Pharmacotherapy. 1998; 18 600-606
- 7 Leo R J, Kim K Y. Clomipramine treatment of paraphilias in elderly demented patients. J Geriatr Psychiatry Neurol. 1995; 8 23-124
- 8 Lothstein L M, Fogg-Waberski J, Reynolds P. Risk management and treatment of sexual disinhibition in geriatric patients. Conn Med. 1997; 61 609-618
- 9 Stewart J T, Shin K J. Paroxetine treatment of sexual disinhibition in dementia. Am J Psychiatry. 997; 154 1474
- 10 Tariot P N, Erb R, Podgorski C A, Cox0 C, Patel S, Jakimovich L, Irvine C. Efficacy and tolerability of carbamazepine for agitation and aggression in dementia. Am J Psychiatry. 1998; 155 54-61
- 11 Tsai S J, Hwang J P, Yang C H, Liu K M, Lirng J F. Inappropriate sexual behaviors in dementia: a preliminary report. Alzheimer Dis Assoc Disord. 1999; 13 60-62
- 12 Wiseman S V, McAuley J W, Freidenberg G R, Freidenberg D L. Hypersexuality in patients with dementia: Possible response to cimetidine. Neurology. 2000; 54 2024
Dr. F. Jessen
Department of Psychiatry
Friedrich-Wilhelms-University
Sigmund-Freud-Str. 25
53105 Bonn
Germany
Phone: +49 228 287 1109
Fax: +49 228 287 4760
Email: Jessen@uni-bonn.de