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DOI: 10.1055/s-2005-864182
© Georg Thieme Verlag KG Stuttgart · New York
Rotenoids and Isoflavones from Sarcolobus globosus
Publication History
Received: October 14, 2004
Accepted: January 24, 2005
Publication Date:
29 July 2005 (online)
Abstract
Sarcolobus globosus is a medicinal plant growing in mangrove forests in Asia. No constituents from this plant have been reported previously. From the diethyl ether extract of S. globosus a new rotenoid sarcolobin and a new isoflavone sarcolobone, as well as the previously known rotenoids tephrosin, 12aα-hydroxydeguelin, 11-hydroxytephrosin, 12a-hydroxyrotenone, 12aα-hydroxyrotenone, 6aα,12aα-12a-hydroxyelliptone, 6a,12a-dehydrodeguelin, 13-homo-13-oxa-6a,12a-dehydrodeguelin, the isoflavone barbigerone and a chromone 6,7-dimethoxy-2,3-dihydrochromone were identified. 6,7-Dimethoxy-2,3-dihydrochromone has not previously been reported as a natural product.
Key words
Sarcolobus globosus - Asclepiadaceae - rotenoid - isoflavonoid - mangrove forest
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Helle Wangensteen
Department of Pharmacognosy
School of Pharmacy
University of Oslo
P. O. Box 1068 Blindern
0316 Oslo
Norway
Phone: +47-22-85-65-49
Fax: +47-22-85-75-05
Email: helle.wangensteen@farmasi.uio.no