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Synlett 2005(7): 1197-1198
DOI: 10.1055/s-2005-865222
DOI: 10.1055/s-2005-865222
SPOTLIGHT
© Georg Thieme Verlag Stuttgart · New York
Lithium Bromide: A Versatile Reagent in Organic Synthesis
Further Information
Publication History
Publication Date:
14 April 2005 (online)
Introduction
Lithium bromide is used as a sedative and a hypnotic (LD50 = 1800 mg/kg) in medicine and due to its highly hygroscopic property, it is widely used as an operating medium for air-conditioning and industrial drying systems. Since it is a stable and relatively safe compound, lithium bromide is used in various organic transformations such as Biginelli, Knoevenagel, and Wadsworth-Emmons reactions, brominations, dithioacetalizations, and dehydrohalogenations.
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