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Thorac Cardiovasc Surg 2005; 53(6): 389-390
DOI: 10.1055/s-2005-865687
Case Report

© Georg Thieme Verlag KG Stuttgart · New York

Successful Use of Recombinant Factor VIIa in a Patient with Intractable Bleeding During Extracorporeal Membrane Oxygenation

S. Brose1 , 2 , H. Sirbu2 , M. Engel2 , R. Kuhlen3 , R. Autschbach2
  • 1Department of Cardiac Surgery, Heart Center Dresden, University of Dresden, Dresden, Germany
  • 2Department of Cardiothoracic and Vascular Surgery, University Hospital of Aachen, Aachen, Germany
  • 3Department of Anaesthesiology, University Hospital of Aachen, Aachen, Germany
Further Information

Publication History

Received January 30, 2005

Publication Date:
28 November 2005 (online)

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Abstract

Bleeding is still the most common complication during extracorporeal membrane oxygenation (ECMO) for temporary cardio-circulatory support. We present a case of a young man suffering from intractable hemorrhage during ECMO support, who was pre-treated with glycoprotein IIb/IIIa receptor antagonist Tirofiban due to a suspicion of myocardial ischemia. After failure of conventional hemostatic means, hemostasis was achieved by the donation of recombinant Factor VIIa (rFVIIa). Aspects of bleeding control during extracorporeal circulatory support, the use of Tirofiban and rFVIIa are discussed.

Key words

Recombinant Factor VIIa - extracorporeal membrane oxygenation (ECMO) - bleeding - Tirofiban

References

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S. Brose

Department for Cardiac Surgery, Heart Center Dresden, University of Dresden

Fetscherstraße 76

01307 Dresden

Germany

Phone: + 493514501609

Fax: + 49 35 14 50 17 07

Email: s.brose@herzzentrum-dresden.com