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Geburtshilfe Frauenheilkd 2005; 65(9): 844-849
DOI: 10.1055/s-2005-865701
Übersicht

Georg Thieme Verlag KG Stuttgart · New York

Oxytocinfunktionen außerhalb der Schwangerschaft

Oxytocin Functions outside PregnancyT. H. Lippert1 , H. Seeger1 , A. O. Mueck1
  • 1Universitäts-Frauenklinik Tübingen
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Publikationsverlauf

Eingang Manuskript: 21.2.2005 Eingang revidiertes Manuskript: 3.3.2005

Akzeptiert: 2.5.2005

Publikationsdatum:
14. Juli 2005 (online)

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Zusammenfassung

Lange Zeit galt Oxytocin als ein reines Schwangerschaftshormon, das von der Hypophyse zur Wehenstimulation und Milchejektion abgegeben wird. Zahlreiche wissenschaftliche Arbeiten liegen heute vor, die über Oxytocinfunktionen auch außerhalb der Schwangerschaft berichten. So ist bekannt, dass Oxytocinrezeptoren fast ubiquitär im Organismus vorkommen, Oxytocin auch außerhalb des Gehirns gebildet wird und Oxytocin in verschiedenen Organen spezifische Wirkungen auszuüben in der Lage ist. Obwohl der Großteil der Erkenntnisse auf Ergebnissen von Tierexperimenten basiert, gibt es bereits eine Reihe von Studien, die auf Oxytocinwirkungen auch beim Menschen hinweisen.

Abstract

For a long time, oxytocin was regarded as a pregnancy hormone released by the hypophysis to stimulate labour and milk ejection. However, there are numerous research data indicating functions of oxytocin outside pregnancy. It is now known that oxytocin receptors can occur almost ubiquitously in the organism, that oxytocin is also formed outside of the brain, and that oxytocin has functions in a number of organs. Although the majority of findings are based on the results of animal experiments, there are already a number of studies that indicate similar effects of oxytocin in humans.

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Prof. Dr. T. H. Lippert

Universitäts-Frauenklinik

Calwer Straße 7

72076 Tübingen

Deutschland

eMail: endo.meno@med.uni-tuebingen.de