A Facile Route to Sterically Hindered and Non-Hindered 4′-Aryl-2,2′:6′,2′′-Terpyridines

Abstract

A facile one-pot synthesis of 4′-aryl-2,2′:6′,2′′-terpyridines from aryl aldehydes and 2-acetylpyridine is presented. The synthesis of terpyridines incorporating sterically hindered aryl groups, such as the 9-anthryl group, can also be readily synthesized using this method.

Key words

nitrogen ligands - heterocycles - substituted terpyridines - one-pot reactions

References

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15

Most of the starting aryl aldehydes were purchased from Aldrich. Aldehydes that were not commercial available were synthesized from the corresponding aryl bromides by lithiation and then formylation with dimethylformamide.