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Synthesis 2005(12): 1929-1931
DOI: 10.1055/s-2005-869901
DOI: 10.1055/s-2005-869901
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York
Microwave-Assisted Chemoselective Cleavage of Oximes to Their Corresponding Carbonyl Compounds Using 1,3-Dichloro-5,5-dimethyl-hydantoin (DCDMH) as a New Deoximating Reagent
Further Information
Received
14 January 2005
Publication Date:
18 May 2005 (online)
Publication History
Publication Date:
18 May 2005 (online)
Abstract
In the presence of alkene and alcohol, oximes are converted into their parent carbonyl compounds in good yields when treated with 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) (1), under microwave irradiation. The simple work-up minimizes loss of products.
Keywords
aldehyde - ketone - microwave - oxime - selective
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