Skull Base 2005; 15(2): 109-112
DOI: 10.1055/s-2005-870595
CASE REPORT

Copyright © 2005 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Aspergillus Mastoiditis in a Patient with Systemic Lupus Erythematosus: A Case Report

Kwamena Amonoo-Kuofi1 , Phillipa Tostevin1 , Jeff R. Knight1
  • 1Department of Otorhinolaryngology-Head and Neck Surgery, St. George's Hospital Medical School, London, United Kingdom
Further Information

Publication History

Publication Date:
02 June 2005 (online)

ABSTRACT

Fungal mastoiditis caused by Aspergillus fumigatus predominantly occurs in immunocompromised patients. Invasive temporal bone mycoses are rare. They are usually associated with host immunodeficiency, are difficult to diagnose, and many cases are fatal. Treatment consists of antifungal chemotherapy, surgical debridement, and attempts to control the underlying immunological condition. Published reports describe patients with previous ear pathology and associated facial nerve dysfunction. We report a case in a patient with systemic lupus erythematosus. A good outcome followed surgical debridement and the use of a new triazole antifungal agent, voriconazole. Our patient’s facial nerve function was unaffected. The presence of normal facial nerve function, however, does not exclude the possibility of invasive fungal mastoiditis.

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K. Amonoo-Kuofi

No. 37 Farm Drive, Spring Park

Shirley Surrey CR0 7RA, UK

Email: kakuofi@doctors.org.uk