Acute Intestinal Pseudo-Obstruction (Ogilvie's Syndrome)

Nell Maloney; H. David Vargas

doi:10.1055/s-2005-870890

Clinics in Colon and Rectal Surgery, Table of Contents

Clin Colon Rectal Surg 2005; 18(2): 96-101
DOI: 10.1055/s-2005-870890

Acute Intestinal Pseudo-Obstruction (Ogilvie's Syndrome)

Nell Maloney¹ , H. David Vargas¹ ^, ²

¹Department of Surgery, Eastern Virginia Medical School, Norfolk, Virginia
²Tidewater Surgical Specialists, Colorectal Division, Chesapeake, Virginia

Abstract

ABSTRACT

Acute colonic pseudo-obstruction (ACPO), also known as Ogilvie's syndrome, is a condition characterized by massive colonic distension in the absence of mechanical obstruction. Patients presenting with Ogilvie's syndrome have underlying medical and surgical conditions predisposing them to the syndrome. Ogilvie's syndrome can often be managed by conservative therapy. However, unrecognized and untreated, the continued distension associated with Ogilvie's syndrome can lead to perforation that is associated with a high mortality rate. In this article, the pathophysiology, epidemiology, and treatment options are reviewed.

KEYWORDS

Acute intestinal pseudo-obstruction - Ogilvie's syndrome

Full Text

References

REFERENCES

1 Ogilvie W H. Large intestine colic due to sympathetic deprivation: a new clinical syndrome. Br Med J. 1948; 2 671-673
2 Saunders M D, Kimmey M B. Colonic pseudo-obstruction: the dilated colon in the ICU. Semin Gastrointest Dis. 2003; 14 20-27
3 Law N M, Bharucha A E, Undale A S, Zinmeister A R. Cholinergic stimulation enhances colonic motor activity, transit, sensation in humans. Am J Physiol Gastrointest Liver Physiol. 2001; 281 G1228-G1237
4 Ponec R J, Saunders M D, Kimmey M B. Neostigmine for the treatment of acute colonic pseudo-obstruction. N Engl J Med. 1999; 341 137-141
5 Tenofsky P L, Beamer R L, Smith R S. Ogilvie syndrome as a postoperative complication. Arch Surg. 2000; 135 682-687
6 Vanek V W, Al-Salti M. Acute pseudo-obstruction of the colon (Ogilvie's syndrome): an analysis of 400 cases. Dis Colon Rectum. 1986; 29 203-210
7 Moons V, Coremans G, Tack J. An update on acute colonic pseudo-obstruction (Ogilvie's syndrome). Acta Gastroenterol Belg. 2003; 66 150-153
8 Anuras S, Shirazi S S. Colonic pseudo-obstruction. Am J Gastroenterol. 1984; 79 525-531
9 Delgado-Aros S, Camilleri M. Pseudo-obstruction in the critically ill. Best Pract Res Clin Gastroenterol. 2003; 17 427-444
10 Schermer C R, Hanosh J J, Davis M, Pitcher D E. Ogilvie's syndrome in the surgical patient: a new therapeutic modality. J Gastrointest Surg. 1999; 3 173-177
11 Geller A, Petersen B T, Gostout C J. Endoscopic decompression for acute colonic pseudo-obstruction. Gastrointest Endosc. 1996; 44 144-150
12 Hutchinson R, Griffiths C. Acute colonic pseudo-obstruction: a pharmacologic approach. Ann R Coll Surg Engl. 1992; 74 364-367
13 Amaro R, Rogers A I. Neostigmine infusion: new standard of care for acute colonic pseudo-obstruction?. Am J Gastroenterol. 2000; 95 304-305
14 Trevisani G T, Hyman N H, Church J M. Neostigmine: safe and effective treatment for acute colonic pseudo-obstruction. Dis Colon Rectum. 2000; 43 599-603
15 Loftus C G, Harewood G C, Baron T H. Assessment of predictors of response to neostigmine for acute colonic pseudo-obstruction. Am J Gastroenterol. 2002; 97 3118-3122
16 Stephenson B M, Morgan A R, Salaman J R, Wheeler M H. Ogilvie's syndrome: a new approach to an old problem. Dis Colon Rectum. 1995; 38 424-427
17 Turego-Fuentes F, Munoz-Jiminez F, Del Valle-Hernandez E et al.. Early resolution of Ogilvie's syndrome with intravenous neostigmine. Dis Colon Rectum. 1997; 40 1353-1357
18 Eisen G M, Baron T H, Dominitz J A et al.. Acute colonic pseudo-obstruction. Gastrointest Endosc. 2002; 56 789-792
19 MacColl C, MacCannell K L, Baylis B, Lee S S. Treatment of acute colonic pseudoobstruction with cisapride. Gastroenterology. 1990; 98 773-776
20 Lee J T, Taylor B M, Singleton B C. Epidural anesthesia for acute pseudo-obstruction of the colon (Ogilvie's syndrome). Dis Colon Rectum. 1988; 31 686-691
21 Kukora J S, Dent T L. Colonic decompression of massive nonobstructive cecal dilation. Arch Surg. 1977; 112 512-517
22 Gosche J R, Sharpe J N, Larson G M. Colonoscopic decompression for pseudo-obstruction of the colon. Am Surg. 1989; 55 111-115
23 Bode W E, Beart R W, Spencer R J, Culp C E, Wolff B G, Taylor B M. Colonoscopic decompression for acute pseudo-obstruction of the colon (Ogilvie's syndrome). Am J Surg. 1984; 147 243-245
24 Nano D, Prindiville T, Pauly M, Chow H, Ross K, Trudeau W. Colonoscopic therapy of acute pseudoobstruction of the colon. Am J Gastroenterol. 1987; 82 145-148
25 Groff W. Colonoscopic decompression and intubation of the cecum for Ogilvie's syndrome. Dis Colon Rectum. 1985; 26 503-506
26 Rex D K. Acute colonic pseudo-obstruction (Ogilvie's syndrome). Gastroenterologist. 1994; 2 233-238
27 Sariego J, Matsumoto T, Kerstein M D. Colonoscopically guided tube decompression in Ogilvie's syndrome. Dis Colon Rectum. 1991; 34 720-722
28 Fausel C S, Goff J S. Nonoperative management of acute idiopathic colonic pseudo-obstruction (Ogilvie's syndrome). West J Med. 1985; 143 50-54
29 Corman M L. Colon and Rectal Surgery. 4th ed Philadelphia; Lippincott-Williams and Wilkins 1998
30 Duh Q Y, Way L W. Diagnostic laparoscopy and laparoscopic cecostomy for colonic pseudo-obstruction. Dis Colon Rectum. 1993; 36 65-70
31 Casola G, Withers C, vanSonnenberg E, Herba M J, Saba R M, Brown R A. Percutaneous cecostomy for decompression of the massively distended cecum. Radiology. 1986; 158 793-794
32 Benacci J C, Wolff B G. Cecostomy: therapeutic indications and results. Dis Colon Rectum. 1995; 38 530-534
33 Ramage J I, Baron T H. Percutaneous endoscopic cecostomy: a case series. Gastrointest Endosc. 2003; 57 752-755

H. David VargasM.D.

Colorectal Division-Tidewater Surgical Specialists

3205 Churchland Blvd., Chesapeake, VA 23321

Email: dv700@aol.com