An Efficient Acid- and Metal-Free One-Pot Synthesis of Benzothiazoles from Carboxylic Acids

Santosh Rudrawar; Atul Kondaskar; Asit K. Chakraborti

doi:10.1055/s-2005-872092

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Synthesis 2005(15): 2521-2526
DOI: 10.1055/s-2005-872092

PAPER

An Efficient Acid- and Metal-Free One-Pot Synthesis of Benzothiazoles from Carboxylic Acids

Santosh Rudrawar, Atul Kondaskar, Asit K. Chakraborti*
National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar, Punjab 160062, India
Fax: +91(172)2214692; e-Mail: akchakraborti@niper.ac.in;

Further Information

Publication History

Received 7 March 2005
Publication Date:
20 July 2005 (online)

Abstract
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Abstract

Carboxylic acids are converted to benzothiazoles in a one-pot reaction with thionyl chloride followed by treatment with 2-aminothiophenol under acid- and catalyst-free conditions.

Key words

benzothiazoles - carboxylic acids - thionyl chloride - 2-aminothiophenol - acid-free - catalyst-free

References

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