Nickel-in-Charcoal (Ni/C): An Efficient Heterogeneous Catalyst for the Construction of C-C, C-N, and C-H Bonds

Abstract

The preparation and use of nickel-in-charcoal as an environmentally benign and inexpensive alternative to solution-based palladium­-catalyzed cross-couplings are described.

Key words

nickel-in-charcoal - heterogeneous catalysis - cross-couplings

References

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20

Microwave-accelerated heterogeneous cross-couplings based on Ni/C catalysis have been successfully used in Negishi, Suzuki, and amination reactions: Lipshutz, B. H.; Frieman, B. A.; Lee, C-T.; Nihan, D.; Taft B. R., manuscript in preparation.