A Facile Stereoselective Synthesis of (Z,E)-2-Silyl-Substituted 1,3-Dienes via Palladium-Catalyzed Cross-Coupling Reaction

Ming-Zhong Cai; Xing-Lin Ye; Ping-Ping Wang

doi:10.1055/s-2005-872174

SHORTPAPER

A Facile Stereoselective Synthesis of (Z,E)-2-Silyl-Substituted 1,3-Dienes via Palladium-Catalyzed Cross-Coupling Reaction

Ming-Zhong Cai*^a, Xing-Lin Ye^a, Ping-Ping Wang^b
^a School of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330027, P. R. China
^b Department of Chemistry, Jiujiang College, Jiujiang 332000, P. R. China
Fax: +86(791)8517500; e-Mail: caimzhong@163.com;

Abstract

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Abstract

(E)-α-Halovinylsilanes undergo palladium-catalyzed cross-coupling reactions with (E)-alkenylzirconium complexes to afford stereoselectively (Z,E)-2-silyl-substituted 1,3-dienes in good yields.

Keywords

palladium catalysis - hydrozirconation - (E)-α-halovinylsilane - 1,3-diene - cross-coupling reaction - stereoselective synthesis

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References

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