Failure of Thromboprophylaxis in Pregnancy Caused by Dual Deficiencies of Protein S and Protein C

Mamoru Morikawa; Hideto Yamada; Emi H. Kato; Shinichiro Wada; Shigenori Suzuki; Noriaki Sakuragi; Hisanori Minakami

doi:10.1055/s-2005-872429

Seminars in Thrombosis and Hemostasis, Inhaltsverzeichnis

Semin Thromb Hemost 2005; 31(3): 261-265
DOI: 10.1055/s-2005-872429

Failure of Thromboprophylaxis in Pregnancy Caused by Dual Deficiencies of Protein S and Protein C

Mamoru Morikawa¹ , Hideto Yamada¹ ^, ² , Emi H. Kato¹ , Shinichiro Wada¹ , Shigenori Suzuki³ , Noriaki Sakuragi¹ , Hisanori Minakami¹

¹Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan
²Associate Professor, Hokkaido University, Sapporo, Japan
³College of Medical Technology, Hokkaido University, Sapporo, Japan

Abstract

ABSTRACT

Protein S and protein C deficiencies are commonly identified biochemical abnormalities associated with a hypercoagulable state; they result in an increased incidence of venous thromboembolism. We report the case of a pregnant woman with dual deficiencies of protein S and protein C, who encountered a venous thromboembolism 7 days postpartum despite of the use of danaparoid.

KEYWORDS

Pregnancy - thrombosis - protein C - protein S - thromboprophylaxis

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Referenzen

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Hideto YamadaM.D. Ph.D.

Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine

Kita-ku N15 W7, Sapporo 060-8638, Japan

eMail: yhideto@med.hokudai.ac.jp