Semin Thromb Hemost 2005; 31(3): 281-283
DOI: 10.1055/s-2005-872432
Copyright © 2005 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Blood Rheology and Risk of Thromboembolism in Adult and Climacteric Women

Shigenori Suzuki1 , Yoshio Hayashi2 , Kazuhiko Matsuno3 , Takanori Moriyama3 , Gaku Suzuki4
  • 1Professor, School of Human Services, Hokkaido Asai-Gakuen University, Ebetsu-City, Hokkaido; present affiliation: School of Human Services, Asai-Gakuen University, Bunkyodai, Japan
  • 2Hayashi Womens Clinic, Sapporo
  • 3College of Medical Technology, Hokkaido University, Sapporo
  • 4Sapporo Social Insurance Hospital, Sapporo, Japan
Further Information

Publication History

Publication Date:
28 July 2005 (online)

ABSTRACT

Increased age is associated with an increased thrombosing tendency, especially deep vein thrombosis and pulmonary embolism. We investigated blood flow in women of various age groups and found that blood flow decreases with advancing age. Because decreased blood flow can lead to platelet and leukocyte activation, it could be related to the pathogenesis of venous thromboembolism with age.

REFERENCES

  • 1 Alshameeri R S, Mammen E F. Clinical experience with the Thrombostat 4000.  Semin Thromb Hemost. 1995;  21(suppl 2) 1-10
  • 2 Clauss A. Gerinnungsphysiologische Schnellmethode zur Bestimmung des Fibrinogens.  Acta Haematol. 1957;  17 237-240
  • 3 Anderson F A, Wheeler H B, Goldberg R J et al.. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism.  Arch Intern Med. 1991;  151 933-938
  • 4 Kniffin W D, Baron J A, Barrett J, Birkmeyer J D, Anderson F A. The epidemiology of diagnosed pulmonary embolism and deep vein thrombosis in the elderly.  Arch Intern Med. 1994;  154 861-866
  • 5 Hamilton P J, Allardyce M A, Ogston D, Dawson A A, Douglas A S. The effect of age upon the coagulation system.  J Clin Pathol. 1974;  27 980-982
  • 6 Bauer K A, Weiss L M, Sparrow D, Yokonas P S, Rosenberg R D. Aging-associated changes in indices of thrombin generation and protein C activation in humans.  J Clin Invest. 1987;  80 1527-1534
  • 7 Mammen E F. Altersabhängige Veränderungen der Blutgerinnung. In: Beller FK Hormonanwendung bei der Frau über 40. Berlin; Grosse Verlag 1990: 85-89
  • 8 Suzuki S, Hayashi Y, Matsuno K, Moriyama T. Problems of aging related to blood coagulation, rheology in women.  J J Obstet Gynecol Neonat Hematol. 2003;  13 53-54
  • 9 Suzuki S, Matsuno K, Kondoh M. Primary hemostasis during women's life cycle measured by Thrombostat 4000.  Semin Thromb Hemost. 1995;  21(suppl 2) 103-105

 Professor
Shigenori SuzukiM.D. Ph.D. 

School of Human Services, Asai-Gakuen University

Ebetsu-City, Bunkyodai 23, 069-8511

Email: juto@asaigakuen.ac.jp