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Planta Med 2006; 72(1): 81-83
DOI: 10.1055/s-2005-873183
DOI: 10.1055/s-2005-873183
Letter
© Georg Thieme Verlag KG Stuttgart · New York
Quercitrin: An Antileishmanial Flavonoid Glycoside from Kalanchoe pinnata
Further Information
Publication History
Received: April 6, 2005
Accepted: June 20, 2005
Publication Date:
10 November 2005 (online)
Abstract
Quercitrin (quercetin 3-O-α-L-rhamnopyranoside), one of the constituents of the biologically active aqueous extract obtained from Kalanchoe pinnata, is demonstrated to be a potent antileishmanial compound (IC50 ≈ 1 μg/mL) with a low toxicity profile. This is the first time that antileishmanial activity is demonstrated for a flavonoid glycoside.
References
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Sônia S. Costa
Núcleo de Pesquisas de Produtos Naturais
Universidade Federal do Rio de Janeiro
21941-590 Rio de Janeiro, RJ
Brazil
Phone: +55-21-2562 6512
Fax: +55-21-2562 6512
Email: sscosta@nppn.ufrj.br