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Synlett 2005(18): 2769-2770
DOI: 10.1055/s-2005-917118
DOI: 10.1055/s-2005-917118
LETTER
© Georg Thieme Verlag Stuttgart · New York
Selective Oxidation of Methylarenes with Pyridinium Chlorochromate
Further Information
Received
15 July 2005
Publication Date:
10 October 2005 (online)
Publication History
Publication Date:
10 October 2005 (online)

Abstract
A simple and selective method for oxidation of methylarenes, using pyridinium chlorochromate (PCC) is described. This reagent can efficiently oxidize methylarenes to the corresponding aldehydes under mild aprotic conditions.
Key words
methylarenes - PCC - benzylic oxidations - aldehydes
- 1
Barton DHR.Hus RAHF.Lester DJ.Ley SV. Tetrahedron Lett. 1979, 3331 - 2
Venkamanaida M.Krishnarao GS. Synth. Commun. 1979, 144 - 3
Santamaria J.Jroundi R. Tetrahedron Lett. 1991, 32: 4291 - 4
Firouzabadi H.Salehi P.Sardarian AR.Seddighi M. Synth. Commun. 1991, 21: 1121 - 5
Syper L. Tetrahedron Lett. 1966, 37: 4493 - 6
Laundon B.Morrison GA.Brooks JS. J. Chem. Soc. D. 1971, 36 - 7
Gupta M.Paul S.Gupta R.Loupy A. Tetrahedron Lett. 2005, 46: 4957 ; and references cited therein - 8
Nishimura T. Org. Synth. 1955, 4: 713 - 9
Kreh RP.Spotnitz RM.Lundquist JT. Tetrahedron Lett. 1987, 28: 1067 - 10
Walling C.Zhao C.Taliwis GM. J. Org. Chem. 1983, 48: 491 - 11
Zhao D.Lee DG. Synthesis 1994, 915 - 12
Potthast A.Rosenau T.Chen C.-L.Gratzl JS. J. Org. Chem. 1995, 60: 4320 -
13a
Lee GL.Ha DS. Bull. Korean Chem. Soc. 1991, 12: 149 -
13b
Aizpurua JM.Juaristi M.Lecea B.Palomo G. Tetrahedron 1985, 41: 2903 - 14
Piancatelli G.Scettri A.Auria MD. Synthesis 1982, 245 -
15a
Rathore R.Saxena N.Chandrasekaran S. Synth. Commun. 1986, 16: 1493 -
15b
Parish EJ.Chitrakorn S.Wei T.-Y. Synth. Commun. 1986, 16: 1371 -
15c
Bonadies F.Bonini C. Synth. Commun. 1988, 18: 1573