High Surface Area MgO as a Highly Effective Heterogeneous Base Catalyst for Michael Addition and Knoevenagel Condensation Reactions

Chunli Xu; Jonathan K. Bartley; Dan I. Enache; David W. Knight; Graham J. Hutchings

doi:10.1055/s-2005-918467

PAPER

High Surface Area MgO as a Highly Effective Heterogeneous Base Catalyst for Michael Addition and Knoevenagel Condensation Reactions

Chunli Xu, Jonathan K. Bartley, Dan I. Enache, David W. Knight, Graham J. Hutchings*
Cardiff University, School of Chemistry, Main Building, Park Place, Cardiff, CF10 3AT, UK
Fax: +44(29)20874075; e-Mail: hutch@cf.ac.uk;

Abstract

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Abstract

Magnesium oxide (MgO), obtained using a novel but simple procedure, was systematically investigated as a heterogeneous base catalyst for reactions taking place in the liquid phase, specifically the Michael addition and the Knoevenagel condensation. The activity of MgO was studied in detail, together with the effects of solvent and substrate on the catalytic activity for each type of reaction. A key finding is that the formation of enols affected the activity of MgO. The experimental results show that the activity of MgO did not change when it was reused and it is an excellent heterogeneous catalyst for the reactions studied.

Key words

Michael addition - Knoevenagel condensation - solvent effect - enol effect - basic catalysis

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