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Synthesis 2005(19): 3301-3310
DOI: 10.1055/s-2005-918475
DOI: 10.1055/s-2005-918475
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of ent-Halimanolides from ent-Halimic Acid
Further Information
Received
1 August 2005
Publication Date:
14 November 2005 (online)
Publication History
Publication Date:
14 November 2005 (online)
Abstract
Three natural ent-halimanolides have been synthesized from ent-halimic acid. Their structures have been confirmed as well as their absolute configurations established. Bestmann methodology has been used for the synthesis of butenolides and for the synthesis of γ-hydroxybutenolides the Boukouvalas method has been employed.
Key words
diterpenes - alkaloids - ent-halimanolides - reduction
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