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Synlett 2005(18): 2731-2734
DOI: 10.1055/s-2005-918921
DOI: 10.1055/s-2005-918921
LETTER
© Georg Thieme Verlag Stuttgart · New York
An Efficient and Mild CuI/l-Proline-Catalyzed Arylation of Acetylacetone or Ethyl Cyanoacetate
Further Information
Received
25 July 2005
Publication Date:
10 October 2005 (online)
Publication History
Publication Date:
10 October 2005 (online)
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Abstract
The coupling reaction of aryl iodides with acetylacetone or ethyl cyanoacetate under catalysis of CuI/l-proline works at relatively mild conditions to provide 3-aryl-2, 4-pentanediones and α-aryl cyanoacetates in moderate to good yields.
Key words
cross coupling - arylation - aryl iodide - catalysis - additive
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