An Efficient and Mild CuI/l-Proline-Catalyzed Arylation of Acetylacetone or Ethyl Cyanoacetate

Yongwen Jiang; Nan Wu; Haihong Wu; Mingyuan He

doi:10.1055/s-2005-918921

LETTER

An Efficient and Mild CuI/l-Proline-Catalyzed Arylation of Acetylacetone or Ethyl Cyanoacetate

Yongwen Jiang*, Nan Wu, Haihong Wu, Mingyuan He
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 North Zhongshan Road, Shanghai, 200062, P. R. of China
Fax: +86(21)62233424; e-Mail: ywjiang@chem.ecnu.edu.cn;

Abstract

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Abstract

The coupling reaction of aryl iodides with acetylacetone or ethyl cyanoacetate under catalysis of CuI/l-proline works at relatively mild conditions to provide 3-aryl-2, 4-pentanediones and α-aryl cyanoacetates in moderate to good yields.

Key words

cross coupling - arylation - aryl iodide - catalysis - additive

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References

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