Esophageal squamous-cell carcinoma is relatively common in alcohol and tobacco abusers,
and it can develop rapidly after liver transplantation. We report the early detection
of an esophageal squamous-cell carcinoma in a patient with alcoholic cirrhosis, diagnosed
during the pre-enlistment work-up that he was undergoing before liver transplantation.
This lesion had not been detected at standard endoscopy, but was well characterized
using in vivo staining and microscopic examination with an “endocytoscopy” system.
References
- 1
Benlloch S, Berenguer M, Prieto M. et al .
De novo internal neoplasms after liver transplantation: increased risk and aggressive
behavior in recent years?.
Am J Transplant.
2004;
4
596-604
- 2
Herrero J I, Lorenzo M, Quiroga J. et al .
De novo neoplasia after liver transplantation: an analysis of risk factors and influence
on survival.
Liver Transpl.
2004;
11
89-97
- 3
Duvoux C, Delacroix I, Richardet J P. et al .
Increased incidence of oropharyngeal squamous cell carcinomas after liver transplantation
for alcoholic cirrhosis.
Transplantation.
1999;
67
418-421
- 4
Kenngott S, Gerbes A L, Schauer R. et al .
Rapid development of esophageal squamous cell carcinoma after liver transplantation
for alcohol-induced cirrhosis.
Transpl Int.
2003;
16
639-641
- 5
Ban S, Toyonaga A, Harada H. et al .
Iodine staining for early endoscopic detection of esophageal cancer in alcoholics.
Endoscopy.
1998;
30
253-257
- 6
Yokoyama A, Ohmori T, Makuuchi H. et al .
Successful screening for early esophageal cancer in alcoholics using endoscopy and
mucosa iodine staining.
Cancer.
1995;
76
928-934
- 7
Muto M, Hironaka S, Nakane M. et al .
Association of multiple Lugol-voiding lesions with synchronous and metachronous esophageal
squamous cell carcinoma in patients with head and neck cancer.
Gastrointest Endosc.
2002;
56
517-521
- 8
Sakashita M, Inoue H, Kashida H. et al .
Virtual histology of colorectal lesions using laser-scanning confocal microscopy.
Endoscopy.
2003;
35
1033-1038
- 9
Inoue H, Kudo S E, Shiokawa A.
Novel endoscopic imaging techniques toward in vivo observation of living cancer cells
in the gastrointestinal tract.
Dig Dis.
2004;
22
334-337
- 10
Inoue H, Igari T, Nishikage T. et al .
A novel method of virtual histopathology using laser-scanning confocal microscopy
in-vitro with untreated fresh specimens from the gastrointestinal mucosa.
Endoscopy.
2000;
32
439-443
J. M. Dumonceau, M.D.
Division of Gastroenterology and Hepatology
Geneva University Hospitals · 24 Rue Micheli-du-Crest · 1205 Geneva · Switzerland
Fax: +41-22-372-9366
eMail: jmdumonceau@hotmail.com