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DOI: 10.1055/s-2006-923803
© Georg Thieme Verlag KG Stuttgart · New York
Recovery from Giant Cell Myocarditis with ECMO Support and Utilisation of Polyclonal Antithymocyte Globulin: A Case Report
Publication History
Received August 14, 2005
Publication Date:
02 June 2006 (online)
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Abstract
Giant cell myocarditis (GCM) is a rare and frequently fatal disorder. Patients suffer of ventricular arrhythmias or congestive heart failure. Here we describe a patient with cardiogenic shock and histological verified GCM. The patient was saved by implantation of extracorporeal membrane oxygeneation (ECMO) device and concomitant application of Rabbit antithymocyte globuline (rATG, Thymoglobulin, Sangstat), cyclosporine, and steroids in the acute event. 12 months after the crisis the patient evidences NYHA class I heart function and only a moderate impairment of heart function (EF 55 %). The novel utilisation of ECMO in GCM related cardiogenic shock and application of rATG have prooven life-saving in this patient. Studies utilizing rATG in the treatment of GCM are warrented.
Key words
Giant cell myocarditis - autoimmunity - rATG - ECMO - myocarditis - VAD - surgery
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Dr. Hendrik Jan Ankersmit
Department of Cardiothoracic Surgery
Medical University of Vienna
Währinger Gürtel 18 - 20
1090 Vienna
Austria
Email: hjankersmit@hotmail.com