Neuropsychological Problems after Paediatric Stroke: Two Year Follow-Up of Swiss Children

J. Pavlovic; F. Kaufmann; E. Boltshauser; A. Capone Mori; D. Gubser Mercati; C.-A. Haenggeli; E. Keller; J. Lütschg; J.-P. Marcoz; G.-P. Ramelli; E. Roulet Perez; T. Schmitt-Mechelke; M. Weissert; M. Steinlin

doi:10.1055/s-2006-923932

Neuropediatrics, Inhaltsverzeichnis

Neuropediatrics 2006; 37(1): 13-19
DOI: 10.1055/s-2006-923932

Original Article

Georg Thieme Verlag KG Stuttgart · New York

Neuropsychological Problems after Paediatric Stroke: Two Year Follow-Up of Swiss Children

J. Pavlovic¹ , F. Kaufmann¹ , E. Boltshauser⁵ , A. Capone Mori⁶ , D. Gubser Mercati¹⁰ , C.-A. Haenggeli³ , E. Keller⁸ , J. Lütschg² , J.-P. Marcoz¹² , G.-P. Ramelli⁷ , E. Roulet Perez⁴ , T. Schmitt-Mechelke⁹ , M. Weissert¹¹ , M. Steinlin¹

¹University Children's Hospital Berne, Switzerland
²University Children's Hospital Bale, Switzerland
³University Children's Hospital Geneva, Switzerland
⁴University Children's Hospital Lausanne, Switzerland
⁵University Children's Hospital Zürich, Switzerland
⁶Children's Hospital Aarau, Switzerland
⁷Children's Hospital Bellinzona, Switzerland
⁸Children's Hospital Chur, Switzerland
⁹Children's Hospital Lucerne, Switzerland
¹⁰Children's Hospital Neuchatel, Switzerland
¹¹Children's Hospital St. Gallen, Switzerland
¹²Children's Hospital Sion, Switzerland

Abstract

Aim: The aim of this study was to obtain information about neurological and cognitive outcome for a population-based group of children after paediatric ischaemic stroke. Methods: Data from the Swiss neuropaediatric stroke registry (SNPSR), from 1. 1. 2000 to 1. 7. 2002, including children (AIS 1) and neonates (AIS 2). At 18 - 24 months after a stroke, a follow-up examination was performed including a history, neurological and neuropsychological assessment. Results: 33/48 children (22 AIS 1, 11 AIS 2) participated in the study. Neurological outcome was good in 16/33. After childhood stroke mean IQ levels were normal (94), but 6 children had IQ < 85 (50 - 82) and neuropsychological problems were present in 75 %. Performance IQ (93) was reduced compared to verbal IQ (101, p = 0.121) due to problems in the domain of processing speed (89.5); auditory short-term memory was especially affected. Effects on school career were common. Outcome was worse in children after right-sided infarction. Children suffering from stroke in mid-childhood had the best prognosis. There was no clear relationship between outcome and localisation of the lesion. After neonatal stroke 7/11 children showed normal development and epilepsy indicated a worse prognosis in the remaining 4. Conclusion: After paediatric stroke neuropsychological problems are present in about 75 % of children. Younger age at stroke as well as an emergence of epilepsy were predictors for worse prognosis.

Key words

Paediatric stroke - cognitive outcome

Volltext

Referenzen

References

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MD Julia Pavlovic

University Children's Hospital
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Switzerland

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