Subscribe to RSS
DOI: 10.1055/s-2006-924093
© Georg Thieme Verlag KG Stuttgart · New York
Prediction of and Risk Factors for Surgical Wound Infection in the Saphenous Vein Harvesting Leg in Patients Undergoing Coronary Artery Bypass
Publication History
Received September 5, 2005
Publication Date:
10 August 2006 (online)
Abstract
Background: Surgical wound infection (SWI) of the leg after saphenous vein harvesting is an important complication of coronary artery bypass graft (CABG) procedures. SWIs may restrict mobility in the postoperative period and increase costs of postoperative hospitalisation and antibiotic treatment. Methods: A total of 356 patients were followed. Surgical risk factors were evaluated for SWI following saphenous vein harvesting, and the effectiveness of an occlusive glycerinated hydrogel dressing in reducing postoperative SWIs was assessed. In addition, the ability of postoperative clinical wound assessment to predict SWI following CABG 30 and 60 days after operation was investigated. Results: The most important risk factor for SWI after saphenous vein harvesting was the use of a monofilament suture for skin closure (glycomer 4-0 Biosyn® Tyco Healthcare, Stockholm, Sweden) (p > 0.001). The hydrogel dressing did not prevent the development of SWIs. The clinical wound assessment showed that wound gap was associated with leg infection, but other signs were poor predictors of SWI. Conclusion: The choice of suture and suturing technique is important to prevent SWI following saphenous vein harvesting. More precise definitions of wound signs are necessary if they are to be used as predictors of SWI.
Key words
Coronary artery bypass graft - surgical wound infection - saphenous vein harvesting - risk factor - sutures - suturing technique - wound dressing - wound evaluation scale
References
- 1 Jenney A WJ, Harrington G A, Russo P L, Spelman D W. Cost of surgical site infections following coronary artery bypass surgery. Aust NZ J Surg. 2001; 71 662-664
- 2 Vuorisala S, Haukipuro K, Pokela R, Syrjala H. Risk features for surgical-site infections in coronary artery bypass surgery. Infect Control Hosp Epidemiol. 1998; 19 240-247
- 3 Swenne C L, Lindholm C, Borowiec J, Carlsson M. Surgical site infections within 60 days of coronary artery bypass graft surgery. J Hosp Infect. 2004; 57 14-24
- 4 Thomas T A, Taylor S M, Crane M M, Cornett W R, Langan E M, Snyder B A, Cull D L. An analysis of limb-threatening lower extremity wound complications after 1090 consecutive coronary artery bypass procedures. Vasc Med. 1999; 4 83-88
- 5 Goldsborough M A, Miller M H, Gibson J, Creighton-Kelly S, Custer C A, Wallop J M, Greene P S. Prevalence of leg wound complications after coronary artery bypass grafting: determination of risk factors. Am J Care. 1999; 8 149-153
- 6 Wong S W, Fernando D, Grant P. Leg wound infections associated with coronary revascularization. Aust NZ J Surg. 1997; 67 689-691
- 7 Paletta C E, Huang D B, Fiore A C, Swartz M T, Rilloraza F L, Gardner J E. Major leg wound complications after saphenous vein harvest for coronary revascularization. Ann Thoracic Surg. 2000; 70 492-497
- 8 Katz S, Izhar M, Mirelman D. Bacterial adherence of surgical sutures. Ann Surg. 1981; 194 35-41
- 9 Chaudhry H R, Bukiet B, Siegel M, Findley T, Ritter A B, Guzelsu N. Optimal patterns for suturing wounds. J Biomech. 1998; 31 653-662
- 10 Hinman C D, Maibach L H. Effect of air exposure and occlusion on experimental human skin wounds. Nature. 1963; 200 377-378
- 11 Nemeth A J. Faster healing and less pain in skin biopsy sites treated with an occlusive dressing. Arch Dermatol. 1991; 127 1679-1683
- 12 Oliveria-Gandia M, Davis S C, Mertz P. Can occlusive dressing composition influence proliferation of bacterial wound pathogens? A compendium of clinical research and practice. Wounds. 1998; 10 4-11
- 13 Wilson A PR, Sturridge M F, Treasure T, Grüneberg R N. A scoring method (ASEPSIS) for postoperative wound infections for use in clinical trials of antibiotic prophylaxis. Lancet. 1986; 8 311-312
- 14 Tegnell A, Arén C, Öhman L. Wound infections after cardiac surgery - a wound scoring system may improve early detection. Scand Cardiovasc J. 2002; 36 60-64
- 15 Hall J C, Hall J L. Evaluation of a wound scoring method for patients undergoing cardiac surgery. J Hosp Infect. 1996; 33 139-144
- 16 Wipke-Tevis D D, Stotts N A, Skov P, Carrieri-Kohlman V. Frequency, manifestations, and correlates of impaired healing of saphenous vein harvest incisions. Heart Lung. 1996; 25 108-116
- 17 Friberg B, Friberg S, Burman L G. Zoned vertical ultraclean operating room ventilation. A novel concept making long side walls unnecessary. Acta Orthop. 1996; 67 578-582
- 18 Tammelin A, Hambraeus A, Ståhle E. Source and route of methicillin-resistant staphylococcus epidermidis transmitted to the surgical wound during cardiothoracic surgery. Possibility of preventing wound contamination by use of special scrub suits. J Hosp Infect. 2001; 47 266-276
- 19 HICPAC . Guideline for prevention of surgical site infection. Infect Control Hosp Epidemiol. 1999; 20 247-278
- 20 Tyco healthcare . www.syneture.com .
- 21 Hanna J R, Giacopelli J A. A review of wound healing and wound dressing products. J Foot Ankle Surg. 1997; 36 2-14
- 22 Wilson A PR, Helder N, Theminimulle S K, Scott G M. Comparison of wound scoring methods for use in audit. J Hosp Infect. 1998; 39 119-126
- 23 Wilson A PR, Weavill C, Burridge J, Kelsey A. The use of the wound scoring method “ASEPSIS” in postoperative wound surveillance. J Hosp Infect. 1990; 16 297-309
- 24 Bailey I S, Karran S E, Toyn K, Rough P, Ranaboldo C, Karran S J. Community surveillance of complications after hernia surgery. BJM. 1992; 304 469-471
- 25 Brown P, Maloy Oddo J PD. Healing signs for surgical wounds. Adv Skin Wound Care. 2002; 15 143
Christine Leo Swenne
Department of Cardiothoracic Surgery · Uppsala University Hospital
OTM divisionen ing 40, 4 tr
751 85 Uppsala
Sweden
Phone: + 46186113994
Fax: + 46 18 50 93 55
Email: christine.leo.swenne@akademiska.se