Intraokulare Entzündung im Kindesalter

U. Pleyer; C. Sengler

doi:10.1055/s-2006-924692

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Klin Monbl Augenheilkd 2006; 223(10): R85-R101
DOI: 10.1055/s-2006-924692

KliMo-Refresher

Georg Thieme Verlag KG Stuttgart · New York

Intraokulare Entzündung im Kindesalter

Diagnostik und DifferenzialdiagnostikU. Pleyer¹ , C. Sengler¹

¹Campus Virchow Klinikum, Augenklinik, Charité, Universitätsmedizin Berlin

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Publikationsverlauf

Publikationsdatum:
25. Oktober 2006 (online)

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Einleitung

Intraokularen Entzündungen im

Intraokulare Entzündungen haben bei Kindern eine schlechtere Prognose als bei Erwachsenen, Gründe dafür sind verzögerte Diagnose und hohe Morbidität.

Kindesalter kommt besondere Bedeutung zu, da sich Klinik, Diagnostik und Behandlung deutlich von Erkrankungen im Erwachsenenalter unterscheiden können. Hohe Morbidität und verzögerte Diagnose führen bei vielen Kindern zu einer schlechteren Prognose gegenüber intraokularen Entzündungen im späteren Lebensalter. Schwere funktionelle Schäden werden bei etwa 20 bis 30 % betroffener Augen angenommen. Rechtzeitiges Erkennen, Kenntnis der Differenzialdiagnosen und adäquate Behandlung sind Voraussetzungen, die Prognose zu verbessern. Die Betreuung sollte in enger Zusammenarbeit mit dem Kinderarzt, gegebenenfalls Kinderrheumatologen erfolgen.

Literatur

1 American Academy of Pediatrics Section on Rheumatology and Section Ophthalmology . Guidelines for ophthalmologic examinations in children with juvenile rheumatoid arthritis. Pediatrics. 1993; 92 295-296

PubMed Suche in Google Scholar
2 Andersson Gare B. Juvenile arthritis - who gets it, where and when? A review of current data on incidence and prevalence. Clin Exp Rheumatol. 1999; 17 367-374

PubMed Suche in Google Scholar
3 Behn D, Petty R E, Schroeder M L, Lee S K, Stewart S, Lyons C. Evaluation of screening guidelines for uveitis in children with chronic arthritis. Arthritis Rheum. 2001; 44 (Suppl) S167

PubMed Suche in Google Scholar
4 Benezra D, Cohen E, Maftzir G. Patterns of intraocular inflammation in children. Bull Soc Belge Ophthalmol. 2001; 279 35-38

PubMed Suche in Google Scholar
5 Benezra D, Cohen E, Maftzir G. Uveitis in children and adolescents. Br J Ophthalmol. 2005; 89 444-448

Crossref PubMed Suche in Google Scholar
6 Berntson L, Andersson Gare B, Fasth A, Herlin T, Kristinsson J, Lahdenne P, Marhaug G, Nielsen S, Pelkonen P, Rygg M. Nordic Study Group: Incidence of juvenile idiopathic arthritis in the Nordic countries. A population based study with special reference to the validity of the ILAR and EULAR criteria. J Rheumatol. 2003; 30 2275-2282

PubMed Suche in Google Scholar
7 Bertelmann E, Velhagen K H, Pleyer U, Hartmann C. Okuläre Toxocariasis: Diagnostische und therapeutische Optionen. Ophthalmologe. 2003; 100 950-954

Crossref PubMed Suche in Google Scholar
8 Cabral D A, Petty R E, Malleson P N. et al . Visual prognosis in children with chronic anterior uveitis and arthritis. J Rheumatol. 1994; 21 2370-2375

PubMed Suche in Google Scholar
9 Cassidy P. Textbook of Pediatric Rheumatology. 4th Edition. Philadelphia; Saunders 2001: 350-395

Suche in Google Scholar
10 Chalom E C, Goldsmith D P, Koehler M A. et al . Prevalence and outcome of uveitis in a regional cohort of patients with juvenile rheumatoid arthritis. J Rheumatol. 1997; 24 2031-2034

PubMed Suche in Google Scholar
11 Cross A G. Uveitis in children. Trans Ophthalmol Soc UK. 1965; 85 409-419

PubMed Suche in Google Scholar
12 Dana M R, Merayo-Lloves J, Schaumberg D A. et al . Visual outcomes prognosticators in juvenile rheumatoid arthritis-associated uveitis. Ophthalmology. 1977; 104 236-244

PubMed Suche in Google Scholar
13 de Boer J, Wulffraat N, Rothova A. Visual loss in uveitis of childhood. Br J Ophthalmol. 2003; 87 879-884

Crossref PubMed Suche in Google Scholar
14 Edelsten C, Lee V, Bentley C R. et al . An evaluation of baseline risk factors predicting severity in juvenile idiopathic arthritis associated uveitis and other chronic anterior uveitis in early childhood. Br J Ophthalmol. 2002; 86 51-56

Crossref PubMed Suche in Google Scholar
15 Edelsten C, Reddy M A, Stanford M R, Graham E M. Visual loss associated with pediatric uveitis in English primary and referral centers. Am J Ophthalomol. 2003; 135 676-680

Crossref PubMed Suche in Google Scholar
16 Forre O, Dobloug J H, Hoyeraal H M, Thorsby E. HLA antigens in juvenile arthritis. Genetic basis for the different subtypes. Arthritis Rheum. 1983; 26 35-38

PubMed Suche in Google Scholar
17 Häberle H, Velhagen K H, Pleyer U. Pseudophakia in children with juvenile arthritis. Ophthalmologe. 1998; 95 823-827

Crossref PubMed Suche in Google Scholar
18 Häfner R, Vogel P. Sarcoidosis of early onset. A challenge for the pediatric rheumatologist. Clin Exp Rheumatol. 1993; 11 685-691

PubMed Suche in Google Scholar
19 Häfner R, Michels H. Psoriatic arthritis in children. Curr Opin Rheumatol. 1996; 8 467-472

PubMed Suche in Google Scholar
20 Heiligenhaus A, Mingels A, Neudorf U, Ganser G. Juvenile idiopathische Arthritis und Uveitis: Screening und antientzündliche Therapie. Klin Monatsbl Augenheilkd. 2002; 220 738-753

Thieme Connect PubMed Suche in Google Scholar
21 Heinz C, Steuhl K P, Heiligenhaus A. Uveitis bei Sarkoidose im Kindesalter. Klin Monatsbl Augenheilkd. 2005; 222 348-352

Thieme Connect PubMed Suche in Google Scholar
22 Hofer M, Southwood T R. Classification of childhood arthritis. Best Pract Res Clin Rheumato. 2002; 16 379-396

PubMed Suche in Google Scholar
23 Hoover D L, Khan J A, Giangiacomo J. Pediatric ocular sarcoidosis. Surv Ophthalmol. 1986; 30 215-228

PubMed Suche in Google Scholar
24 Kadayifcilar S, Eldern B, Turner B. Uveitis in childhood. J Pediatr Ophthalmol Strabismus. 2003; 40 335-340

PubMed Suche in Google Scholar
25 Kanski J J, Shun-Shin A. Systematic uveitis syndromes in childhood: an analysis of 340 cases. Ophthalmology. 1984; 91 1247-1252

PubMed Suche in Google Scholar
26 Kazdan J J, McCulloch J C, Crawford J S. Uveitis in children. Can Med Assoc J. 1967; 96 385-391

PubMed Suche in Google Scholar
27 Key S N, Kimura S J. Iridocyclitis associated with juvenile rheumatoid arthritis. Am J Ophthalmol. 1975; 80 425-429

PubMed Suche in Google Scholar
28 Kimura S J, Hogan M J, Thygeson P. Uveitis in children. AMA Arch Ophthalmol. 1954; 51 80-88

PubMed Suche in Google Scholar
29 Kiessling U, Doring E, Listing J, Meincke J, Schontube M, Strangfeld A, Zink A. Incidence and prevalence of juvenile chronic arthritis in East Berlin 1980 - 1988. J Rheumatol. 1998; 25 1837-1843

PubMed Suche in Google Scholar
30 Koskull von S, Truckenbrodt H, Holle R, Hormann A. Incidence and prevalence of juvenile arthritis in an urban population of southern Germany: a prospective study. Ann Rheum Dis. 2001; 60 940-945

Crossref PubMed Suche in Google Scholar
31 Kotaniemi K, Kautiainen H, Karma A. et al . Occurrence of uveitis in recently diagnosed juvenile chronic arthritis: a prospective study. Ophthalmology. 2001; 108 2071-2075

Crossref PubMed Suche in Google Scholar
32 Kotaniemi K, Kotaniemi A, Savolainen A. Uveitis as a marker of active arthritis in 372 patients with juvenile idiopathic seronegative oligoarthritis or polyarthritis. Clin Exp Rheumatol. 2002; 20 109-112

PubMed Suche in Google Scholar
33 Kump L I, Cervantes-Castaneda R A, Androudi S N, Foster C S. Analysis of pediatric uveitis cases at a tertiary referral center. Ophthalmology. 2005; 112 1287-1292

Crossref PubMed Suche in Google Scholar
34 Lam L A, Lowder C Y, Baerveldt G. et al . Surgical management of cataracts in children with juvenile rheumatoid arthritis-associated uveitis. Am J Ophthalmol. 2003; 135 772-778

Crossref PubMed Suche in Google Scholar
35 Leak A M, Ansell B M. The relationship between ocular and articular disease activity in juvenile rheumatoid arthritis complicated by chronic anterior uveitis. Arthritis Rheum. 1987; 30 1196-1197

PubMed Suche in Google Scholar
36 Makley T A, Long J, Suic T. Uveitis in children. J Pediatr Ophthalmol. 1969; 6 136-139

PubMed Suche in Google Scholar
37 Moorthy Inomata R SH, Rao N A. Vogt-Koyanagi-Harada syndrome. Surv Ophthalmol. 1995; 39 265-292

PubMed Suche in Google Scholar
38 Paivönsalo-Hietanen T, Tuominen J, Saari K M. Uveitis in children: population-based study in Finland. Acta Ophthalmol Scand. 2000; 78 84-88

Crossref PubMed Suche in Google Scholar
39 Perkins E S. Pattern of uveitis in children. Br J Ophthalmol. 1966; 50 169-185

PubMed Suche in Google Scholar
40 Petty R E. Is there a useful model for the study of childhood uveitis and arthritis?. Clin Exp Rheumatol. 1992; 11 7-8

PubMed Suche in Google Scholar
41 Petty R E, Southwood T R, Baum J, Bhettay E, Glass D N, Manners P, Maldonado-Cocco J, Suarez-Almazor M, Orozco-Alcala J, Prieur A M. Revision of the proposed classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol. 1998; 25 1991-1994

PubMed Suche in Google Scholar
42 Petty R E, Smith J R, Rosenbaum J T. Arthritis and uveitis in children. A pediatric rheumatology perspective. Am J Ophthalmol. 2003; 135 879-884

Crossref PubMed Suche in Google Scholar
43 Pivetti-Pezzi P. Uveitis in children. Eur J Ophthalmol. 1996; 6 293-298

PubMed Suche in Google Scholar
44 Pleyer U, Velhagen K H, Scherer M. et al .Intraokularlinsen - Implantation bei Uveitis, assoziiert mit kinderrheumatologischen Erkrankungen. 13. Kongreß der DGII. Köln; Biermann-Verlag 2000: 29-36

Suche in Google Scholar
45 Pleyer U, Priem S, Bergmann L, Burmester G, Hartmann C, Krause A. Detection of Borrelia burgdorferi DNA in urine of patients with ocular Lyme borreliosis. Br J Ophthalmol. 2001; 85 552-555

Crossref PubMed Suche in Google Scholar
46 Pleyer U, Sengler C, Orlic N, Keitzer R. The Tip of the iceberg: Current knowledge of uveitis in juvenile arthritis. Pleyer U, Mondino BJ Essential in Ophthalmology. Uveitis and immunological disorders. Berlin; Springer Verlag 2004: 125-140

Suche in Google Scholar
47 Probst L E, Holland E J. Intraocular lens implantation in patients with juvenile rheumatoid arthritis. Am J Ophthalmol. 1996; 122 161-170

PubMed Suche in Google Scholar
48 Quentin C D, Reiber H. Fuchs heterochromic cyclitis: rubella virus antibodies and genome in aqueous humor. Am J Ophthalmol. 2004; 138 46-54

Crossref PubMed Suche in Google Scholar
49 Read R W, Holland G N, Rao N A. et al . Revised diagnostic criteria for Vogt-Koyanagi-Harada disease report of an international committee on nomenclature. Am J Ophthalmol. 2001; 131 647-652

Crossref PubMed Suche in Google Scholar
50 Rieger R, Keitzer R, Pleyer U. Vogt-Koyanagi-Harada-Syndrom: Seltene Differenzialdiagnose der Uveitis im Kindesalter. Klin Monatsbl Augenheilkd. 2005; 222 919-922

Thieme Connect PubMed Suche in Google Scholar
51 Rosenberg K D, Feuer W J, Davis J L. Ocular complications of pediatric uveitis. Ophthalmology. 2004; 111 2299

Crossref PubMed Suche in Google Scholar
52 Scholz S, Albert E D. Immunogenetic aspects of juvenile chronic arthritis. Clin Exp Rheumatol. 1993; 11 37-41

PubMed Suche in Google Scholar
53 Sengler C, Keitzer R, Pleyer U. Intraokulare Entzündung bei rheumatologischen Erkrankungen im Kindesalter. Ophthalmologe. 2005; 102 463-476

Crossref PubMed Suche in Google Scholar
54 Southwood T R, Petty R E, Malleson P N, Delgado E A, Hunt D W, Wood B, Schroeder M L. Psoriatic arthritis in children. Arthritis Rheum. 1989; 32 1007-1013

Crossref PubMed Suche in Google Scholar
55 Soylu M, Ozdemir G, Anli A. Pediatric uveitis in southern Turkey. Ocul Immunol Inflamm. 1997; 5 197-202

PubMed Suche in Google Scholar
56 Stoffel P B, Sauvain M J, von Vigier R O. et al . Non-infectious causes of uveitis in 70 Swiss children. Acta Paediatr. 2000; 8 955-958

PubMed Suche in Google Scholar
57 Symmons D P, Jones M, Osborne J. et al . Pediatric rheumatology in the United Kingdom: data from the rheumatology group national register. J Rheumatol. 1996; 23 1975-1980

PubMed Suche in Google Scholar
58 Torun N, Liekfeld A, Hartmann C, Metzner S, Pleyer U. Okuläre Toxoplasmose-Antikörper in Kammerwasser und Serum. Ophthalmologe. 2002; 99 109-112

Crossref PubMed Suche in Google Scholar
59 Torun N, Callizo J, Orlic N, Scherer M, Hartmann C, Pleyer U. Serum cytokine receptor levels in noninfectious uveitis. Ophthalmic Res. 2005; 37 112-116

Crossref PubMed Suche in Google Scholar
60 Tugal-Tutkun I, Havrlikova K, Power W J, Foster C S. Changing patterns in uveitis of childhood. Ophthalmology. 1996; 103 375-383

PubMed Suche in Google Scholar
61 Tugal-Tutkun I, Urgancioglu M. Childhood-onset uveitis in Behcet disease: a descriptive study of 36 cases. Am J Ophthalmol. 2003; 136 1114-1119

Crossref PubMed Suche in Google Scholar
62 Wolf M D, Lichter P R, Ragsdale C G. Prognostic factors in the uveitis of juvenile rheumatoid arthritis. Ophthalmology. 1987; 94 1242-1248

PubMed Suche in Google Scholar
63 Zulian F, Martini G, Falcini F. et al . Early predictors of severe course of uveitis in oligoarticular juvenile idiopathic arthritis. J Rheumatol. 2002; 29 2446-2453

PubMed Suche in Google Scholar

Prof. Dr. med. U. Pleyer

Augenklinik
Charité
Universitätsmedizin Berlin
Campus Virchow Klinikum

Augustenburger Platz 1

13353 Berlin

eMail: uwe.pleyer@charite.de