Synthesis 2006(4): 675-679  
DOI: 10.1055/s-2006-926300
PAPER
© Georg Thieme Verlag Stuttgart · New York

Pyridinium Ylides in the Synthesis of 2,3-Dihydrofurans

Che-Ping Chuang*, An-I Tsai
Department of Chemistry, National Cheng Kung University, Tainan, Taiwan 70101, Taiwan
Fax: +886(6)2740552; e-Mail: cpchuang@mail.ncku.edu.tw;
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Publikationsverlauf

Received 4 August 2005
Publikationsdatum:
11. Januar 2006 (online)

Abstract

A new method for the synthesis of 2,3-dihydrofurans from readily available starting enones and pyridinium salts has been developed. This protocol can provide a novel and effective methodology for the preparation of 2,3-dihydrofurans in a stereoselective fashion. To increase the efficiency of this reaction the one-pot process was also developed, in which the pyridinium salts were generated in situ from corresponding halides.