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DOI: 10.1055/s-2006-931576
Aeruginascin, a Trimethylammonium Analogue of Psilocybin from the Hallucinogenic Mushroom Inocybe aeruginascens
Dedicated to Dr. Albert Hofmann in honour of his 100th birthdayPublikationsverlauf
Received: November 10, 2005
Accepted: February 3, 2006
Publikationsdatum:
28. April 2006 (online)
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Abstract
The hallucinogenic mushroom Inocybe aeruginascens contains several typical Psilocybe alkaloids including psilocybin. We have now elucidated the structure of a further indole derivative named aeruginascin as the quaternary ammonium compound N,N,N-trimethyl-4-phosphoryloxytryptamine. Aeruginascin is closely related to the frog skin toxin bufotenidine (5-HTQ), a potent 5-HT3 receptor agonist, and has been found exclusively in Inocybe aeruginascens so far.
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Prof. Dr. Hartmut Laatsch
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Georg-August University Göttingen
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