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Dtsch Med Wochenschr 2006; 131(16): 892-895
DOI: 10.1055/s-2006-939865
DOI: 10.1055/s-2006-939865
Prinzip & Perspektive | Review article
Regenerative Medizin, Rheumatologie,Immunologie
© Georg Thieme Verlag KG Stuttgart · New York
Mesenchymale Stammzellen zur Geweberegeneration und zur Immunsuppression
Tissue regeneration and immunosuppression by mesenchymal stem cellsFurther Information
Publication History
eingereicht: 22.11.2005
akzeptiert: 22.3.2006
Publication Date:
20 April 2006 (online)

Schlüsselwörter
Mesenchymale Stammzellen - Abstoßungsreaktion
Key words
mesenchymal stem cells - Graft-versus-Host-Disease
Literatur
- 1 Aggarwal S, Pittenger M F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 2005; 105 1815-1822
- 2 Devine S M, Cobbs C, Jennings M, Bartholomew A, Hoffman R. Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates. Blood. 2003; 101 2999-3001
- 3 Djouad F, Fritz V, Apparailly F. et al . Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis. Arthritis Rheum. 2005; 52 1595-1603
- 4 Djouad F, Plence P, Bony C. et al . Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. Blood. 2003; 102 3837-3844
- 5 Fouillard L, Bensidhoum M, Bories D. et al . Engraftment of allogeneic mesenchymal stem cells in the bone marrow of a patient with severe idiopathic aplastic anemia improves stroma. Leukemia. 2003; 17 474-476
- 6 Frassoni F, Labopin M, Bacigalupo A. Expanded mesenchymal stem cells (MSC), co-infused with HLA-identical hematopoietic stem cell transplants, reduce acute and chronic graft-versus-host disease: a matched pair analysis (abstract 75). Bone Marrow Transplant. 2002; (suppl 2) 29 S2
- 7 Horwitz E M, Gordon P L, Koo W K. et al . Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone. Proc Natl Acad Sci U S A. 2002; 99 8932-8937
- 8 Ishida T, Inaba M, Hisha H. et al . Requirement of donor-derived stromal cells in the bone marrow for successful allogeneic bone marrow transplantation. J Immunol. 1994; 152 3119-3127
- 9 Jorgensen C, Djouad F, Fritz V, Apparailly F, Plence P, Noel D. Mesenchymal stem cells and rheumatoid arthritis. Joint Bone Spine. 2003; 70 483-485
- 10 Koc O N, Day J, Nieder M. et al . Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH). Bone Marrow Transplant. 2002; 30 215-222
- 11 Koc O N, Gerson S L, Cooper B W. et al . Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol. 2000; 18 307-316
- 12 Le Blanc K, Gotherstrom C, Ringden O. et al . Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta. Transplantation. 2005; 79 1607-1614
- 13 Le Blanc K, Rasmusson I, Sundberg B. et al . Treatment of severe acute graft-versus-host disease with third partly haploidentical mesenchymal stem cells. Lancet. 2004; 363 1439-1441
- 14 Le Blanc K, Ringden O. Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2005; 11 321-334
- 15 Wagner W, Wein F, Seckinger A. et al . Comparative characterization of mesenchymal stem cells from human bone marrow, adipose tissue and umbilical cord blood. Exp Hematol. 2005; 33 1402-1416
- 16 Lazarus H M. et al . Ex vivo expansion and subsequent infusion of human bone-marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic use. Bone Marrow Transplantation. 1995; 16 557
Prof. Dr. Hanns-Martin Lorenz
Sektion Rheumatologie, Medizinische Klinik V, Universität Heidelberg
Im Neuenheimer Feld 410
69120 Heidelberg
Phone: 06221-568044
Fax: 06221-566824
Email: hannes.lorenz@med.uni-heidelberg.de