Pharmacopsychiatry 2006; 39(3): 111-112
DOI: 10.1055/s-2006-941485
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Aripiprazole Pharmacotherapy of Borderline Personality Disorder

A Series of Three Consecutive Case ReportsA. Mobascher1 , J. Mobascher1 , V. Schlemper1 , G. Winterer1 , J. Malevani1
  • 1Department of Psychiatry, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany
Further Information

Publication History

Received: 26.9.2005 Revised: 2.1.2006

Accepted: 9.1.2006

Publication Date:
23 May 2006 (online)

We report three consecutive cases of women with borderline personality disorder with psychotic symptoms, who received pharmacotherapy with the new atypical antipsychotic drug aripiprazole. Therapeutic effects were measured using the SCL-90R (symptom check list) and the BSL (borderline symptom list). We observed different responses to aripiprazole. In the first patient we had to discontinue the drug before we were able to observe any therapeutic effects. The second patient also complained about initial side effects. However, after the dose was lowered, the drug was tolerated and she responded well to aripiprazole with respect to all psychopathological aspects. The third patient did not suffer from any side effects under aripiprazole. She responded partially to the drug. Aripiprazole may have a potential role in the pharmacotherapy of borderline personality disorder and may not only target psychotic symptoms in these patients.

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Dr. Arian Mobascher

Department of Psychiatry

Heinrich-Heine-University Düsseldorf

Bergische Landstr. 2

40629 Düsseldorf

Germany

Email: arian.mobascher@lvr.de