Anal Melanoma

Marc Singer; Matthew G. Mutch

doi:10.1055/s-2006-942348

Clinics in Colon and Rectal Surgery, Inhaltsverzeichnis

Clin Colon Rectal Surg 2006; 19(2): 078-087
DOI: 10.1055/s-2006-942348

Anal Melanoma

Marc Singer¹ , Matthew G. Mutch¹

¹Section of Colon and Rectal Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri

Abstract

ABSTRACT

Anal melanoma is rare and aggressive malignancy. Patients commonly present with advanced, even metastatic disease. Unlike cutaneous melanoma, anal melanoma has no known risk factors. Surgical excision remains the cornerstone of therapy. There are no long-term survivors of stage II or III disease; therefore, early diagnosis and treatment remain crucial. There are no trials definitively proving abdominal perineal resection (APR) or wide local excision (WLE) to yield superior long-term survival. APR may offer a higher rate of local control, whereas WLE offers a much less morbid operation. Adjuvant chemotherapy, interferon, and radiation may offer some benefit.

KEYWORDS

Melanoma - anal - malignancy - abdominoperineal resection - wide local excision

Volltext

Referenzen

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Matthew G MutchM.D.

Section of Colon and Rectal Surgery, Department of Surgery, Washington University School of Medicine

660 S. Euclid Ave., Box 8109, St. Louis, MO 63110-1010

eMail: mutchm@wudosis.wustl.edu