CAN-Mediated Oxidative Addition of 1,3-Dicarbonyl Compounds to Methylenecyclopropanes: A Facile Synthesis of Spirocyclopropyl Dihydrofurans

Abstract

1,3-Dicarbonyl compounds react with methylenecyclopropanes by oxidation with CAN to give spirocyclopropyl dihydrofuran derivatives in good yields.

Key words

CAN - methylenecyclopropanes - 1,3-dicarbonyl compounds - dihydrofurans - oxidative addition

References

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10

This is not surprising, as we have reported that MeOH is the ideal solvent for CAN-mediated addition of active methylene compounds to alkenes (see ref. 7).