Abstract
Regioselective intermolecular radical carboaminoxylation using various alkoxyamines are presented. These environmentally benign tin-free radical additions can either be performed under microwave conditions at 180 °C or by using conventional heating at 125 °C. Intermolecular Trost-Tsuji allylation of the carboaminoxylation products provide five- and six-membered carbocycles in moderate to good yields. The radical addition/Pd-catalyzed intramolecular allylation can be performed as one-pot process.
Key words
radical chemistry - nitroxides - allylations - Pd catalysis
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