Fokal-segmentale Glomerulosklerose (FSGS)

fokal-segmentale
Glomerulosklerose - nephrotisches Syndrom - Podozyten

focal segmental
glomerulosclerosis - nephrotic syndrome - podocytes

Literatur

• 1 D’Agati V D, Fogo A B, Bruijn J A, Jenette J C. Pathologic classification of focal segmental glomerulosclerosis: a working proposal.  Am J Kidney Dis. 2004;  43 368-382
• 2 Massague J. How cells read TGF-beta signals.  Nat Rev Mol Cell Biol. 2000;  1 169-178
• 3 Schiffer M, Bitzer M, Roberts I SD. et al . Apoptosis in podocytes induced by TGF-beta and Smad7.  J Clin Invest. 2001;  108 807-816
• 4 Vincenti F, Ghiggeri G M. New insights into the pathogenesis and the therapy of recurrent focal glomerulosclerosis.  Am J Transplant. 2005;  5 1179-1185
• 5 Wharram B L, Goyal M, Wiggins J E. et al . Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene.  J Am Soc Nephrol. 2005;  16 2941-2952