A man affected by schizoaffective disorder and alcohol abuse presented priapism after eleven years of clozapine treatment. After surgical intervention and resolution of priapism, he continued clozapine treatment at the same dose without problems. Clozapine withdrawal is not mandatory in patients who develop priapism in the course of treatment.
References
-
1
Barbieri NB, Dube JM.
Clozapine and priapism: an association to consider.
Can J Psychiatry.
1994;
39
128
-
2
Bongale RN, Tekell JL, Haraguchi GE, Navarro EM.
Continuation of clozapine after priapism.
Am J Psychiatry.
2001;
158
2087
-
3
Compton MT, Miller AH.
Priapism associated with conventional and atypical antipsychotic medications: a review.
J Clin Psychiatry.
2001;
62
362-366
-
4
Compton MT, Saldivia A, Berry SA.
Recurrent priapism during treatment with clozapine and olanzapine.
Am J Psychiatry.
2000;
157
659
-
5
de Nesnera A.
Successful treatment with clozapine at higher doses after clozapine-induced priapism.
J Clin Psychiatry.
2003;
64
1394-1395
-
6
Harmon WJ, Nehra A.
Priapism: diagnosis and management.
Mayo Clin Proc.
1997;
72
350-355
-
7 Hashmat AI, Rehman JU. Priapism. In: Hashmat AI, Das S (eds.) The Penis. Lea & Febiger Philadelphia; 1993: 219-243
-
8
Hovermann P, Nurnbach-Ross B, Albrecht J.
Priapism with clozapine therapy.
Nervenarzt.
1997;
68
74-76
-
9
Melman A, Serels S.
Priapism.
Int J Imp Res.
2000;
12
((Suppl 4))
133-139
-
10
Moinfar N, Goad S, Brink DD, Klinger RL.
Clozapine-related priapism.
Hosp Commun Psychiatry.
1994;
45
1044
-
11
Pryor J, Akkus E, Alter G, Jordan G, Lebret T, Levine L, Mulhall J, Perovic S, Ralph D, Stackl W.
Priapism.
J Sex Med.
2004;
1
116-120
-
12
Raja M, Altavista MC, Maisto G, Albanese A.
Tardive dystonia treated with clozapine.
Mov Disord.
1996;
11
585-586
-
13
Reeves RR, Mack JE.
Priapism associated with two atypical antipsychotic agents.
Pharmacotherapy.
2002;
22
1070-1073
-
14
Rosen SI, Hanno PM.
Clozapine-induced priapism.
J Urol.
1992;
148
876-877
-
15
Seftel AD, Saenz de Tejada I, Szetela B, Cole J, Goldstein I.
Clozapine-associated priapism: a case report.
J Urol.
1992;
147
146-148
-
16
Spycher MA, Hauri D.
The ultrastructure of the erectile tissue in priapism.
J Urol.
1986;
135
142-147
-
17
Wang CS, Kao WT, Chen CD, Tung YP, Lung FW.
Priapism associated with typical and antipsychotic medications.
Int Clin Psychopharmacol.
2006;
21
245-248
Correspondence
Michele RajaM.D.
Servizio Psichiatrico di Diagnosi e Cura
Ospedale Santo Spirito·via Prisciano 26·00136 Rome·Italy
Phone: (mob) +39/34 73 42 21 58
Fax: +39/06/589 87 21
Email: michele.raja@libero.it
Email: michele.raja@fastwebnet.it
