Synthesis 2006(20): 3490-3494  
DOI: 10.1055/s-2006-949464
PAPER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Cyclic Enehydrazides by Ring-Closing Metathesis

Stéphane Lebrun, Axel Couture*, Eric Deniau, Pierre Grandclaudon
UMR 8009 ‘Chimie Organique et Macromoléculaire’, Laboratoire de Chimie Organique Physique, Université des Sciences et Technologies de Lille, Bâtiment C3(2), 59655 Villeneuve d’Ascq Cedex, France
Fax: +33(3)20336309; e-Mail: axel.couture@univ-lille1.fr;
Further Information

Publication History

Received 16 May 2006
Publication Date:
10 October 2006 (online)

Abstract

A series of five- and six-membered unsaturated hydrazides were efficiently prepared from precursor dienehydrazides through a ring-closing metathesis (RCM) reaction. The parent compounds were easily obtained by sequential acylation and alkylation of appropriate hydrazines.