Synthesis of (-)-(5R,6S)-6-Acetoxyhexadecanolide, a Mosquito Oviposition Attractant­ Pheromone of Culex pipiens fatigans [1]

Abstract

Asymmetric total synthesis of (-)-(5R,6S)-6-acetoxyhexadecanolide has been achieved via a key intermediate which was prepared by a Grignard reaction from an alcohol. The alcohol was easily accessed via two different routes.

lactone - total synthesis - natural product - (-)-(5R,6S)-6-acetoxyhexadecanolide - pheromone

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