Subscribe to RSS
DOI: 10.1055/s-2006-950393
© Georg Thieme Verlag KG Stuttgart · New York
Cotrimoxazole-induced Psychosis: A Case Report and Review of Literature
Publication History
Received 6. 3. 2006
Revised 3. 7. 2006
Accepted 7. 7. 2006
Publication Date:
23 November 2006 (online)
We present a case of acute psychosis in a 46-year-old woman who had been treated orally with cotrimoxazole because of a severe infection of the urinary tract. She had started to develop psychotic symptoms with bizarre behavior two days before admission. Following discontinuation of antibiotic therapy, including cessation of treatment with cotrimoxazole and the induction of antipsychotic treatment, her mental state resolved to a stable premorbid level within 36 hours.
References
- 1 Gregor JC, Zilli CA, Gotlib IH. Acute psychosis associated with oral trimethoprim-sulfamethoxazole therapy. Can J Psychiatry. 1993; 38 56-58
- 2 Howe RA, Spencer RC. Cotrimoxazole. Rationale for re-examining its indications for use. Drug Saf. 1996; 14 213-218
- 3 McCue JD, Zandt JR. Acute psychoses associated with the use of ciprofloxacin and trimethoprim-sulfamethoxazole. Am J Med. 1991; 90 528-529
- 4 Mermel LA, Doro JM, Kabadi UM. Acute psychosis in a patient receiving trimethoprim-sulfamethoxazole intravenously. J Clin Psychiatry. 1986; 47 269-270
- 5 Saidinejad M, Ewald MB, Shannon MW. Transient psychosis in an immune-competent patient after oral trimethoprim-sulfamethoxazole administration. Pediatrics. 2005; 115 e739-e741
- 6 Sternbach H, State R. Antibiotics: neuropsychiatric effects and psychotropic interactions. Harv Rev Psychiatry. 1997; 5 214-226
Correspondence
Stefanie Weis
Klinik mit Poliklinik für Psychiatrie und Psychotherapie
Universitätsklinikum Erlangen
Schwabachanlage 6
D-91054 Erlagen
Phone: +49/91/31 85 34 166
Fax: +49/91/31 85 34 862
Email: stefanie.weis@psych.imed.uni-erlangen.de