Chemistry has been developed that allows for the synthesis of a series of novel tricyclic
thioxanthen-9-one-10,10-dioxides. A regioselective synthesis of the novel core substrate
3-chlorothioxanthen-9-one-10,10-dioxide was achieved in 85% yield over three steps
without the need for chromatographic purification. Subsequent microwave-assisted coupling
methodology afforded the desired novel 3-substituted tricyclic compounds in good to
excellent yield.
catalysis - heterocycles - palladium - Suzuki reaction - thioxanthenone dioxide
