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Planta Med 2006; 72(15): 1418-1420
DOI: 10.1055/s-2006-951704
DOI: 10.1055/s-2006-951704
Letter
© Georg Thieme Verlag KG Stuttgart · New York
5α-Cardenolides from Kanahia laniflora Inhibit Ionotropic Acetylcholine Receptors
Further Information
Publication History
Received: May 9, 2006
Accepted: August 21, 2006
Publication Date:
20 October 2006 (online)
Abstract
5α-Cardenolides isolated from Kanahia laniflora are inhibitors of muscle-type nicotinic acetylcholine receptors expressed in TE671 cells with IC50 values in the range of 27 - 60 μM, as determined by whole-cell patch-clamp electrophysiological experiments.
- Supporting Information for this article is available online at
- Supporting Information .
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Prof. Jerzy W. Jaroszewski
Department of Medicinal Chemistry
The Danish University of Pharmaceutical Sciences
Universitetsparken 2
2100 Copenhagen
Denmark
Fax: +45-3530-6040
Email: jj@dfuni.dk
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