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DOI: 10.1055/s-2006-951942
Neurobiologie alkoholbedingten Suchtverhaltens
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Die neurobiologischen Grundlagen von Alkoholkrankheiten sind von vergleichbar großer Relevanz wie die psychosozialen Grundlagen dieser Erkrankungen.
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Alkoholwirkungen sind für nahezu alle Neurotransmittersysteme belegt.
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Eine verminderte Reaktion der biologischen Regelkreisläufe auf eine akute Alkoholgabe ist sehr häufig ein Risikofaktor für die Entwicklung einer Alkoholkrankheit.
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Suchtgedächtnis und reizassoziiertes Suchtverlangen spielen bei der langfristigen Alkoholentwöhnung eine größere Rolle als körperliche Entzugssymptome.
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Die vorhandenen medikamentösen Optionen bei der Behandlung der Alkoholabhängigkeit sollten genutzt werden, da eine Wirksamkeit gut belegt ist.
Publikationsverlauf
Publikationsdatum:
16. April 2007 (online)
© Georg Thieme Verlag KG Stuttgart · New York
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Einleitung
Genetische Zusammenhänge
Neurotransmitter
Langfristige neurobiologische Auswirkungen
Die Rolle neuroendokriner Peptide
Therapeutische Konsequenzen