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Semin Reprod Med 2006; 24(5): 358-369
DOI: 10.1055/s-2006-952150
Copyright © 2006 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Stem Cells from Umbilical Cord Blood

Juan Sanchez-Ramos1
  • 1Department of Neurology, University of South Florida, Tampa, Florida
Further Information

Publication History

Publication Date:
22 November 2006 (online)

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ABSTRACT

The study of hematopoiesis, the generation of blood cell lines throughout life, has provided conceptual, experimental, and therapeutic approaches useful to all stem cell biologists. From a clinical perspective, no other area of stem cell biology has been applied as successfully as has transplantation of bone marrow and cord blood for the treatment of blood diseases. In the last few years, research in stem cell biology has expanded rapidly to include the study of stem cells from embryonic, fetal, and various adult tissues, engendering novel perspectives regarding the identity, origin, and full therapeutic potential of tissue-specific stem cells. Rather than focusing on the use of cord blood stem cells for reconstitution of bone marrow, this article reviews the biology of stem cells found in the cord blood in the context of cell plasticity and their therapeutic potential for repair of the nervous system.

KEYWORDS

Stem cells - umbilical cord blood - plasticity - central nervous system

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Juan Sanchez-RamosM.D. 

Department of Neurology (MDC 55), University of South Florida

12901 Bruce B. Downs Blvd., Tampa, FL 33612

Email: jsramos@hsc.usf.edu