Am J Perinatol 2007; 24(1): 017-021
DOI: 10.1055/s-2006-954960
Copyright © 2007 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Are Routine Cranial Ultrasounds Necessary in Premature Infants Greater Than 30 Weeks Gestation?

N. Ja'Neice Harris1 , Diana Palacio2 , Andrew Ginzel3 , C. Joan Richardson1 , Leonard Swischuk2
  • 1Division of Neonatology, University of Texas Medical Branch, Galveston, Texas
  • 2Department of Radiology, University of Texas Medical Branch, Galveston, Texas
  • 3Senior Medical Student, University of Texas Medical Branch, Galveston, Texas
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
08. November 2006 (online)

ABSTRACT

The purpose of this study was to validate the recommendation of the American Academy of Neurology and the Child Neurology Society that screening cranial ultrasonography be performed routinely on all infants of less than 30 weeks gestation at 7 to 14 days of age and again between 36 and 40 weeks postmenstrual age, and, by using this practice parameter, to determine the number of babies with a clinically significant abnormal screening cranial ultrasound (US) who would otherwise have been missed. A retrospective study of 486 infants of 30 to 33 weeks gestation born January 1, 1999 to June 30, 2004 was done. All had screening cranial ultrasounds. Grade III and/or grade IV intraventricular hemorrhage (IVH) occurred in 4 (0.8%) infants of 30 to 31 weeks gestation. Infants with significant IVH had either risk factors for brain injury or symptoms that would eventually warrant US during their hospitalization. Seven (1.4%) infants had periventricular leukomalacia (PVL). All infants with a final diagnosis of PVL had pre- and/or perinatal risk factors associated with PVL. There was a significant trend toward fewer abnormal cranial ultrasounds from 30 to 33 weeks gestation (p = 0.04). Our study supports the recommendation by the American Academy of Neurology and the Child Neurology Society that screening US can be limited but suggests that the gestational age cut off should be 30 weeks or less.

REFERENCES

  • 1 Ment L R, Bada H S, Barnes P et al.. Practice parameter: neuroimaging of the neonate. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society.  Neurology. 2002;  58 1726-1738
  • 2 Fanaroff A A, Martin R J. Intracranial hemorrhage. In: Papile, L-A Neonatal-Perinatal Medicine. Diseases of the Fetus and Infant. St. Louis, MO; Mosby 2002: 879-881
  • 3 Rezaie P, Dean A. Periventricular leukomalacia, inflammation and white matter lesions within the developing nervous system.  Neuropathology. 2002;  22 106-132
  • 4 Volpe J J. Brain injury in the premature infant-from pathogenesis to prevention.  Brain Dev. 1997;  19 519-534
  • 5 Ment L R, Vohr B, Allan W et al.. The etiology and outcome of the cerebral ventriculomegaly at term in very low birth weight preterm infants.  Pediatrics. 1999;  104 243-248
  • 6 Papile L S, Burstein J, Burstein R, Koffler H. Incidence and evolution of the subependymal intraventricular hemorrhage: a study of infants with weights less than 1500 grams.  J Pediatr. 1978;  92 529-534
  • 7 Boal D K, Watterberg K L, Miles S, Gifford K L. Optimal cost-effective timing of cranial ultrasound screening in low-birth weight infants.  Pediatr Radiol. 1995;  25 425-428
  • 8 Perlman J, Rollins N. Surveillance protocol for the detection of intracranial abnormalities in premature neonates.  Arch Pediatr Adolesc Med. 2000;  154 822-826
  • 9 Batton D, Holtrop P, DeWitte D, Pryce C, Roberts C. Current gestational age-related incidence of major intraventricular hemorrhage.  J Pediatr. 1994;  125 623-625
  • 10 Harding D, Kuschel C, Evans N. Should preterm infants born after 29 weeks' gestation be screened for intraventricular hemorrhage?.  J Paediatr Child Health. 1998;  34 57-59
  • 11 Behrman R, Kliegman R, Jenson H. The nervous system. In: Haslam R Nelson Textbook of Pediatrics. Philadelphia, PA; WB Saunders 2000: 1795
  • 12 Holzman C, Paneth N, Little R, Pinto-Martin J. Neonatal Brain Hemorrhage Study Team . Perinatal brain injury in premature infants born to mothers using alcohol in pregnancy.  Pediatrics. 1995;  95 66-72

 Dr.
N. Ja'Neice Harris

301 University Blvd, Route 0526

Galveston, TX 77555

    >