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DOI: 10.1055/s-2006-956445
Reoperation for Recurrent Colorectal Cancer
Publication History
Publication Date:
24 November 2006 (online)
ABSTRACT
Recurrence of colorectal carcinoma represents a significant challenge. As the majority of recurrences involve more than just the anastomosis, surgical resection is ordinarily a major undertaking. Curative resection may require resection of other organs and structures, resulting in complex reconstructive procedures and substantial morbidity. In addition, carefully selected patients with distant metastases to sites such as the liver and lungs may also undergo potentially curative resection. Long-term survival following curative surgery for recurrence, however, ranges from only 15 to 40%. In addition to resection for curative intent, some patients may benefit from palliative procedures designed to relieve symptoms. Surgery alone is not usually sufficient therapy in these patients. Chemotherapy and radiation therapy play a vital adjunctive role in the management of recurrent disease. This article strives to review the risk factors and patterns of recurrence, selection of individuals for resection of recurrent disease, and outcomes of surgical procedures.
KEYWORDS
Colorectal neoplasm - recurrence - surgery - metastatic
REFERENCES
- 1 Fuzun M, Terzi C, Sokmen S, Unek T, Haciyanli M. Potentially curative resection for locoregional recurrence of colorectal cancer. Surg Today. 2004; 34 907-912
- 2 Meyers M, Sasson A, Sigurdson E. Locoregional strategies for colorectal hepatic metastasis. Clin Colorectal Cancer. 2003; 3 34-44
- 3 Bowne W, Lee B, Wong W et al.. Operative salvage for locoregional recurrent colon cancer after curative resection: an analysis of 100 cases. Dis Colon Rectum. 2005; 48 897-909
- 4 Devesa J, Morales V, Enriquez J. Colorectal cancer: the basis for a comprehensive follow up. Dis Colon Rectum. 1988; 31 636-652
- 5 Waldron R, Donovan I. Clinical follow up and treatment of locally recurrent colorectal cancer. Dis Colon Rectum. 1987; 30 428-430
- 6 Shumate C, Rich T, Skibber J, Ajani J, Ota D. Preoperative chemotherapy and radiation therapy for locally advanced primary and recurrent rectal carcinoma. Cancer. 1993; 71 3690-3696
- 7 Galandiuk S, Wieand H, Moertel C et al.. Patterns of recurrence after curative resection of carcinoma of the colon and rectum. Surg Gynecol Obstet. 1992; 174 27-32
- 8 Shibata D, Paty P, Guillem J, Wong W, Cohen A. Surgical management of isolated retroperitoneal recurrences of colorectal carcinoma. Dis Colon Rectum. 2002; 45 795-801
- 9 Penna C, Nordlinger B. Colorectal metastasis (liver and lung). Surg Clin North Am. 2002; 82 1075-1090
- 10 Rodriguez-Bigas M, Stulc J, Davidson B, Petrelli N. Prognostic significance of anastomotic recurrence from colorectal adenocarcinoma. Dis Colon Rectum. 1992; 35 838-842
- 11 Willett C, Tepper J, Cohen A, Orlow E, Welch C. Obstructive and perforative colonic carcinoma: patterns of failure. J Clin Oncol. 1985; 3 379-384
- 12 Obrand D, Gordon P. Incidence and patterns of recurrence following curative resection for colorectal carcinoma. Dis Colon Rectum. 1997; 40 15-24
- 13 Sagar P, Pemberton J. Surgical management of locally recurrent rectal cancer. Br J Surg. 1996; 83 293-304
- 14 Adloff M, Arnaud J, Schloegel M, Thibaud D. Factors influencing local recurrence after abdominoperineal resection for cancer of the rectum. Dis Colon Rectum. 1985; 28 413-415
- 15 Willett C G, Tepper J E, Cohen A M, Orlow E, Welch C E. Failure patterns following curative resection of colonic carcinoma. Ann Surg. 1984; 200 685-690
- 16 Malcolm A W, Perencevich N P, Olson R M, Hanley J A, Chaffey J T, Wilson R E. Analysis of recurrence patterns following curative resection for carcinoma of the colon and rectum. Surg Gynecol Obstet. 1981; 152 131-136
- 17 Steele G. Standard postoperative monitoring of patients after primary resection of colon and rectum cancer. Cancer. 1993; 71 4225-4235
- 18 Goldberg R, Fleming T, Tangen C et al.. Surgery for recurrent colon cancer: strategies for identifying resectable recurrence and success rates after resection. Ann Intern Med. 1998; 129 27-35
- 19 Bruinvels D J, Stiggelbout A M, Kievet J. Follow-up of patients with colorectal cancer. A meta-analysis. Ann Surg. 1994; 219 174-182
- 20 Agrawal J, Syngal S. Colon cancer screening strategies. Curr Opin Gastroenterol. 2005; 21 59-63
- 21 Lucha P, Rosen L, Olenwine J et al.. Value of carcinoembryonic antigen monitoring in curative surgery for recurrent colorectal carcinoma. Dis Colon Rectum. 1997; 40 145-149
- 22 Moertel C G, Fleming T R, Macdonald J S, Haller D G, Laurie J A, Tangen C. An evaluation of the carcinoembryonic antigen (CEA) test for monitoring patients with resected colon cancer. JAMA. 1993; 270 943-947
- 23 Khoury D, Opelka F, Beck D, Hicks T, Timmcke A, Gathright J. Colon surveillance after colorectal cancer surgery. Dis Colon Rectum. 1996; 39 252-255
- 24 Takeuchi O, Saito N, Koda K, Sarashina H, Nakajima N. Clinical assessment of positron emission tomography for the diagnosis of local recurrence in colorectal cancer. Br J Surg. 1999; 86 932-937
- 25 Desai D, Zervos E, Arnold M, Burak W, Mantil J, Martin E. Positron emission tomography affects surgical management in recurrent colorectal cancer patients. Ann Surg Oncol. 2003; 10 59-64
- 26 Sheikh F, Khubchandani I. Prophylactic ureteric catheters in colon surgery-how safe are they? Report of three cases. Dis Colon Rectum. 1990; 33 508-510
- 27 Maetani S, Nishikawa T, Iijima Y. Extensive en bloc resection of regionally recurrent carcinoma of the rectum. Cancer. 1992; 69 2876-2883
- 28 Gwin J, Hoffman J, Eisenberg B. Surgical management of nonhepatic intra-abdominal recurrence of carcinoma of the colon. Dis Colon Rectum. 1993; 36 540-544
- 29 Minton J P, Hoehn J L, Gerber D M. Results of a 400 patient carcinoembryonic antigen second look colorectal cancer study. Cancer. 1985; 55 1284-1290
- 30 Kendal W, Cripps C, Viertelhausen S, Stern H. Multimodality management of locally recurrent colorectal cancer. Surg Clin North Am. 2002; 82 1059-1073
- 31 Koea J, Lanouette N, Paty P, Guillem J, Cohen A. Abdominal wall recurrence after colorectal resection for cancer. Dis Colon Rectum. 2000; 43 628-632
- 32 Stellato T A, Shenk R R. Gastrointestinal emergencies in the oncological patient. Semin Oncol. 1989; 16 521-531
- 33 Henry L, Sigurdson E, Ross E, Hoffaman J. Hydronephrosis does not preclude curative resection of pelvic recurrences after colorectal surgery. Ann Surg Oncol. 2005; 12 786-792
- 34 Larsen S, Wiig J, Giercksky K E. Hydronephrosis as a prognostic factor in pelvic recurrence from rectal and colon carcinomas. Am J Surg. 2005; 190 55-60
- 35 Pilipshen S J, Heilweil M, Quan S H, Sternberg S S, Enker W E. Patterns of pelvic recurrence following definitive resections of rectal cancer. Cancer. 1984; 53 1354-1362
- 36 Guillem J, Ruo L. Strategies in operative therapy for locally recurrent rectal cancer. Semin Colon Rectal Surg. 1998; 9 259-268
- 37 Moore H, Shoup M, Riedel E et al.. Colorectal cancer pelvic recurrences: determinants of resectability. Dis Colon Rectum. 2004; 47 1599-1606
- 38 Wanebo H, Antoniuk P, Koness J et al.. Pelvic resection of recurrent rectal cancer. Dis Colon Rectum. 1999; 42 1438-1448
- 39 Suzuki K, Dozois R R, Devine R M et al.. Curative reoperation for locally recurrent rectal cancer. Dis Colon Rectum. 1996; 39 730-736
- 40 Hartley J E, Lopez R A, Paty P B, Wong W D, Cohen A M, Guillem J G. Resection of locally recurrent colorectal cancer in the presence of distant metastases: can it be justified?. Ann Surg Oncol. 2003; 10 227-233
- 41 Maetani S, Nishikawa T, Iijima Y, Tobe T. Extensive en bloc resection of regionally recurrent carcinoma of the rectum. Cancer. 1992; 69 2876-2883
- 42 Hoffman J P, Riley L, Carp N Z, Litwin S. Isolated locally recurrent rectal cancer: a review of incidence, presentation and management. Semin Oncol. 1993; 20 506-519
- 43 Kroll S S, Pollock R, Jessup J M, Ota D. Transpelvic rectus abdominis flap reconstruction of defects following abdominal perineal resection. Am Surg. 1989; 55 632-637
- 44 Shoup M, Guillem J, Alektiar K et al.. Predictors of survival in recurrent rectal cancer after resection and intraoperative radiotherapy. Dis Colon Rectum. 2002; 45 585-592
- 45 Hashiguchi Y, Sekine T, Sakamoto H, Tanaka Y. Intraoperative irradiation after surgery for locally recurrent rectal cancer. Dis Colon Rectum. 1999; 42 886-895
- 46 Kuehne J, Kleisli T, Biernacki P et al.. Use of high dose rate brachytherapy in the management of locally recurrent rectal cancer. Dis Colon Rectum. 2003; 46 895-899
- 47 Jimenez R, Shoup M, Cohen A, Paty P, Guillem J, Wong D. Contemporary outcomes of total pelvic exenteration in the treatment of colorectal cancer. Dis Colon Rectum. 2003; 46 1619-1625
- 48 Rodel C, Grabenbauer G, Matzel K et al.. Extensive surgery after high dose preoperative chemoradiotherapy for locally advanced recurrent rectal cancer. Dis Colon Rectum. 2000; 43 312-319
- 49 Mannaerts G, Rutten H, Martijn H, Hanssens P, Wiggers T. Comparison of intraoperative radiation therapy-containing multimodality treatment with historical treatment modalities for locally recurrent rectal cancer. Dis Colon Rectum. 2001; 44 1749-1758
- 50 Ohhigashi S, Nishio T, Watanabe F, Matsusako M. Experience with radiofrequency ablation in the treatment of pelvic recurrence in rectal cancer. Dis Colon Rectum. 2001; 44 741-745
- 51 Law W L, Chu K W, Ho J W, Tung H M, Law S Y, Chu K M. Self expanding metallic stent in the treatment of colonic obstruction caused by advanced malignancies. Dis Colon Rectum. 2000; 43 1522-1527
- 52 Ekberg H, Tranberg K G, Andersson R et al.. Determinants of survival in liver resection for colorectal secondaries. Br J Surg. 1986; 73 727-731
- 53 Lehnert T, Knaebel H P, Duck M, Bulzebruck H, Herfarth C. Sequential hepatic and pulmonary resections for metastatic colorectal cancer. Br J Surg. 1999; 86 241-243
- 54 Taschieri A M, Elli M, Vignatti G A et al.. Repeated liver resection for recurrent metastases form colorectal cancer. Hepatogastroenterology. 2003; 50 472-474
- 55 Ruers T J, Joosten J, Jager G J, Wobbes T. Long-term results of treating hepatic colorectal metastases with cryosurgery. Br J Surg. 2001; 88 844-849
- 56 Ike H, Shimada H, Ohki S, Togo S, Yamaguchi S, Ichikawa Y. Results of aggressive resection of lung metastases from colorectal carcinoma detected by intensive follow up. Dis Colon Rectum. 2002; 45 468-475
- 57 Higashiyama M, Kodama K, Higaki N et al.. Surgery for pulmonary metastases from colorectal cancer-the importance of prethoracotomy serum carcinoembryonic antigen as an indicator of prognosis. Jpn J Thorac Cardiovasc Surg. 2003; 51 289-296
- 58 Banerjee S, Kapur S, Moran B J. The role of prophylactic oophorectomy in women undergoing surgery for colorectal cancer. Colorectal Dis. 2005; 7 214-217
- 59 Sielezneff I, Salle E, Antoine K, Thirion X, Brunet C, Sastre B. Simultaneous bilateral oophorectomy does not improve prognosis of postmenopausal women undergoing colorectal resection for cancer. Dis Colon Rectum. 1997; 40 1299-1302
- 60 Young-Fadok T M, Wolff B G, Nivatvongs S, Metzger P P, Ilstrup D M. Prophylactic oophorectomy in colorectal carcinoma: preliminary results of a randomized, prospective trial. Dis Colon Rectum. 1998; 41 277-285
- 61 Morrow M, Enker W E. Late ovarian metastases in carcinoma of the colon and rectum. Arch Surg. 1984; 119 1385-1388
- 62 Boey J, Cheung H C, Lai C K, Wong J. A prospective evaluation of serum carcinoembryonic antigen (CEA) levels in the management of colorectal carcinoma. World J Surg. 1984; 8 279-286
Michael D HellingerM.D.
DeWitt Daughtry family Department of Surgery, Division of Colon and Rectal Surgery, University of Miami, Miller School of Medicine
1475 NW 12th Ave., Rm. 3550, Miami, FL 33136
Email: mhelling@med.miami.edu