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Planta Med 1998; 64(5): 482-483
DOI: 10.1055/s-2006-957493
Letters

© Georg Thieme Verlag Stuttgart · New York

Supercritical Carbon Dioxide Extraction of Podophyllotoxin from Dysosma pleiantha Roots

Young Hae Choi1 , Jung Yeon Kim1 , Jung Hwan Ryu2 , Ki-Pung Yoo2 , Yuan Shiun Chang3 , Jinwoong Kim1
  • 1College of Pharmacy, Seoul National University, Seoul, Republic of Korea
  • 2Department of Chemical Engineering, Sogang University, Seoul, Republic of Korea
  • 3China Medical College, Taichung, Republic of China
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Publikationsverlauf

1997

1998

Publikationsdatum:
04. Januar 2007 (online)

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Abstract

Supercritical fluid extraction (SFE) was utilized to extract podophyllotoxin from the roots of Dysosma pleiantha. The extraction was carried out in the temperature range of 40-80 °C and the pressure range of 13.6-34.0 MPa with supercritical carbon dioxide. However, podophyllotoxin was not sufficiently extracted by pure supercritical carbon dioxide. Methanol was used as modifier to enhance the extraction yield of podophyllotoxin. As a result, SFE produced a higher recovery of podophyllotoxin than conventional 95% ethanol extraction.