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Planta Med 1997; 63(1): 55-57
DOI: 10.1055/s-2006-957604
Papers
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

Chemical Constituents of Isatis indigotica

Xiaoyun Wu1 , Yunhai Liu2 , Wanyun Sheng3 , Jie Sun4 , Guowei Qin1
  • 1Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China
  • 2Tongji Affiliated Hospital, Tongji Medical University, Wuhan 430030, China
  • 3Shanghai Institute of Planned Parenthood Research, Shanghai 200032, China
  • 4Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
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Publication History

1996

1996

Publication Date:
04 January 2007 (online)

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Abstract

From the roots of Isatis indigotica, ten compounds (1-10) were isolated. Compound 1 is a new alkaloid whose structure was elucidated as (E)-3-(3′,5′-dimethoxy-4′-hydroxy-benzylidene)-2-indolinone. Compounds 2-4 were discovered for the first time from a natural source and compounds 5-7 were originally isolated from this species. In a preliminary study, compounds 4-8 showed antiendotoxic activities in vitro.

Key words

Isatis indigotica - Cruciferae - (E)-3-(3′,5′-dimethoxy-4′-hydroxybenzylidene)-2-indolinone - antiendotoxic activity