Chinchona Alkaloid from Dendrosenecio kilimanjari subsp. cottonii

Obuya Were; Michael Benn; Raphael Munavu

doi:10.1055/s-2006-957616

Planta Medica, Inhaltsverzeichnis

Planta Med 1997; 63(1): 90-92
DOI: 10.1055/s-2006-957616

Letters

Chinchona Alkaloid from Dendrosenecio kilimanjari subsp. cottonii

Obuya Were¹ ^, ³ , Michael Benn¹ , Raphael Munavu²

¹University of Calgary, Calgary, Alberta, Canada, T2N, 1N4
²Department of Chemistry, Univ. of Nairobi, P.O. Box 30197 Nairobi, Kenya
³Egerton University, Department of Chemistry, P.O. Box 536, Njoro, Kenya

Abstract

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Abstract

Investigation of the Tanzanian Dendrosenecio kilimanjari subsp. cottonii resulted in the isolation of the cinchona alkaloid, cinchonidine (2). Conversion of cinchonidine to deoxy-cinchonidine was achieved in high yield using zinc dust in aqueous sulphuric acid. This illustrates the first reduction of a quinoline system using these reagents.

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