New Flavonoids from the Aerial Parts of Aconitum chiisanense

Abstract

The studies were carried out to evaluate the constituents in the aerial part of Aconitum chiisanense (Ranunculaceae). From the butanol fraction of the methanol extract, kaempferol 3-O-β-glucopyranoside-7-O-(6-trans-caffeoyl)-β-glucopyranosyl-(1→2)-α-rhamnopyranoside (I), quercetin 3-O-β-glucopyranoside-7-O-(6-trans-caffeoyl)-β-glucopyranosyl-(1→2)-α-rhamnopyranoside (II), kaempferol 3-O-β-glucopyranoside-7-O-(6-trans-feruloyl)-β-glucopyranosyl-(1→2)-α-rhamnopyranoside (III), kaempferol 3-O-β-glucopyranoside-7-O-(6-benzoyl)-β-glucopyranosyl-(1→2)-α-rhamnopyranoside (IV), kaempferol 7-O-(6-trans)-caffeoyl)-β-glucopyranosyl-(1→2)-α -rhamnopyranoside (V), and kaempferol 7-O-β-glucopyranosyl-(1→2)-α-rhamnopyranoside (VI) were isolated and identified on the basis of their physicochemical and spectroscopic evidence (UV, IR, FAB(-)MS, ¹H-NMR, ¹³C-NMR, ¹H-¹H COSY, HMQC and HMBC). New compounds I-VI were named chiisanin (I), chiiribanin (II), chiiribaconin (III), chiirin (IV), chiiricanin (V), and chiirirhamnin (VI), respectively.

Key words

Aconitum chiisanense - Ranunculaceae - flavonoids - kaempferol derivatives - quercetin derivatives - chiisanin - chiiribanin - chiiribaconin - chiirin - chiiricanin - chiirirhamnin